The Risk of Second Primary Gastrointestinal Malignancies Following Primary Gastrointestinal Carcinoid Tumors: a SEER Based Study 2000-2022

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

93481 participants

Study Classification

OBSERVATIONAL

Study Start Date

2000-12-01

Study Completion Date

2022-12-30

Brief Summary

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Carcinoid tumors are rare neuroendocrine tumors with slowly progressive course. Carcinoid tumors are the most common gastrointestinal (GI) neuroendocrine tumors. The most common sites of GI carcinoids are small intestine accounting for 45%, rectum (20%), appendix (17%), colon (11%), and stomach (7%). Some studies reported an association between neuroendocrine tumors and multiple malignancies. However, the presence of neuroendocrine tumors combined with multiple primary GI tumors is considered an exotic event in the literature with only few case studies and case series. So the aim of this study is to assess the risk of GI malignancies following primary GI carcinoids.

Detailed Description

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Carcinoid tumors are rare neuroendocrine tumors with slowly progressive course. Carcinoid tumors are the most common gastrointestinal (GI) neuroendocrine tumors. The most common sites of GI carcinoids are small intestine accounting for 45%, rectum (20%), appendix (17%), colon (11%), and stomach (7%). Some studies reported an association between neuroendocrine tumors and multiple malignancies. However, the presence of neuroendocrine tumors combined with multiple primary GI tumors is considered an exotic event in the literature with only few case studies and case series. So the aim of this study is to assess the risk of GI malignancies following primary GI carcinoids.

Conditions

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Carcinoid Tumor Second Primary Malignant Neoplasm

Keywords

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SEER Carcinoid malignancy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients diagnosed with gastrointestinal carcinoid tumor.
* patients diagnosed from 2000 till 2022

Exclusion Criteria

* patients diagnosed with autopsy only or death certificate only.
* patients lacking age documentation.

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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asmaa salama ibrahim

Resident physician of gastroenterology

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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A276

Identifier Type: -

Identifier Source: org_study_id