WELT-REST: WELT Randomized Evaluation of Sleep Therapy

NCT ID: NCT07289217

Last Updated: 2025-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-31

Study Completion Date

2026-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this clinical trial is to learn whether the SleepQ mobile app can help reduce insomnia symptoms in adults diagnosed with insomnia. The main questions it aims to answer are:

* Does adding the SleepQ app to care as usual (CAU) improve insomnia symptoms after 12 weeks?
* Does SleepQ also improve depressive symptoms, anxiety, beliefs about sleep and daily functioning?

Researchers will compare CAU + SleepQ to CAU alone to see whether SleepQ provides additional benefits for sleep and well-being.

Participants will take part remotely from home, be randomly assigned to either SleepQ+CAU or CAU alone, and complete online questionnaires at baseline, week 6, and week 12 about their sleep, mood, and daily functioning.

Participants in the intervention group will use the SleepQ app for 12 weeks while continuing their usual care.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

SleepQ is digital CBT-I application developed to align with national clinical guidelines for the treatment of sleep disorders. The program includes psychoeducation, sleep restriction therapy, stimulus control, sleep hygiene approaches, cognitive restructuring, and relaxation exercises. The app also incorporates a digital sleep diary, personalized sleep timing recommendations, interactive learning modules, quizzes to reinforce concepts, and monitoring of therapy progress. The overall design aims to support engagement and autonomous adherence to CBT-I principles by providing step-by-step guidance and feedback throughout the therapeutic course.

The pilot clinical trial will evaluate the effectiveness of SleepQ as an add-on to care as usual (CAU) compared with CAU alone in adults diagnosed with insomnia. Approximately 80 adult participants with a confirmed diagnosis of insomnia will be enrolled and randomized in a 1:1 ratio to the intervention group (SleepQ + CAU) or the control group (CAU alone). The study will be conducted as a fully decentralized trial within Germany. Screening, informed consent, eligibility confirmation, randomization, and all outcome assessments will be conducted remotely. Participants will complete self-reported questionnaires at baseline, week 6, and week 12 to assess changes in insomnia severity and related symptoms.

The primary endpoint is the reduction in insomnia symptoms after 12 weeks, and secondary outcomes include changes in depressiv symptoms, anxiety, dysfunctional beliefs about sleep, and daily functioning.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Insomnia

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

dCBT - I CBT - I Insomnia Cognitive Behavioral Therapy Sleep Disorder Digital Therapeutics Digital CBT - I

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

SleepQ Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)

Group Type EXPERIMENTAL

SleepQ Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)

Intervention Type BEHAVIORAL

SleepQ is a fully digital, individualized 12-week cognitive behavioral therapy program for adults with insomnia. The intervention is delivered via the SleepQ mobile application and includes structured CBT-I components such as sleep restriction therapy, stimulus control, psychoeducation, cognitive restructuring, sleep hygiene training, and daily sleep diary input, in addition to Care-as-Usual (CAU).

Care-as-Usual (CAU)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

SleepQ Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)

SleepQ is a fully digital, individualized 12-week cognitive behavioral therapy program for adults with insomnia. The intervention is delivered via the SleepQ mobile application and includes structured CBT-I components such as sleep restriction therapy, stimulus control, psychoeducation, cognitive restructuring, sleep hygiene training, and daily sleep diary input, in addition to Care-as-Usual (CAU).

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adult patients ≥18 years old
* Confirmed current diagnosis of F51.0 Nonorganic insomnia or G47.0 Sleep disorders
* Possession of a mobile device with internet connection (must be run on iOS software, minimum version 18) with internet connection
* Sufficient German language proficiency required for the correct use of the intervention and the mobile device
* Personal e-mail address for registration
* Willing and able to provide written informed consent
* Insomnia Severity Index (ISI) socre of 15 or higher, indicating clinically relevant symptoms of insomnia
* Registered with a GP, sleep specialist or other health care professional

Exclusion Criteria

* Use of a digital interventioan for insomnia treatment in the past 6 months or planned use of comparable digital intervention during the study period
* PHQ-9 score at screening ≥ 20 and/or item 9 f PHQ-9 ≥ 1
* GAD-7 score at screening ≥ 15
* Intermittent use and/or recent initiation (\< 3m) or planned use of insomnia specific prescription-only pharmacological therapy
* Intermittent use and/or recent initiation (\< 3m) or planned use of a psychotropic during the study period which has recognised potential effects on insomnia
* Participation in CBT or other psychotherapy to treat sleep disorders in the last 6 months (outpatient, inpatient) or planned start during the study period
* Known history or diagnosis of substance or alchol abuse or dependence within 12 months prior to screening (diagnosis of F10-F19, excluding F17.1 and F17.2)
* Current or planned participation in other clinical trials during the study period
* Working in shifts
* Currently pregnant or planning to become pregnant within the next 3 months
* Any surgical procedure that was scheduled, planned, or conducted within the timeframe of the study (minor outpatient procedures under local anaesthetic or with no anesthetic are permitted)
* Diagnosis of epilepsy
* Presence of serious mental illness, such as (schizophrenia F 20.-, acute transient psychotic disorders F23.-, active manic episode F30.-, bipolar disorder F31.-, severe depression F32.3, F33.3)
* Other diseases (such as acute or severe cardiac diseases, acute or severe respiratory diseases, acute or severe gastrointestinal diseases), conditions or therapies which, in the opinion of the investigator, could confound the study results or contraindicate participation.
* Acute suicidal thoughts or intentions within the past 12 months
* Presence of obstructive sleep apnea, restless legs syndrome, parasomnia, and other sleep behavior problem
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

WELT corp

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Berlin Medical Association (Ärztekammer Berlin)

Berlin, , Germany

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Yujin Lee

Role: CONTACT

Phone: +82-2-6439-0707

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Ethics Committee of the Berlin Medical Association

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

WCTP-DI-A-01

Identifier Type: -

Identifier Source: org_study_id