Ultrasound Assesment Of Radial Nerve In Humeral Shaft Fracture Patients With Radial Palsy

NCT ID: NCT07286734

Last Updated: 2025-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2026-02-28

Brief Summary

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This study investigates how well ultrasound imaging can identify damage to the radial nerve in patients with a broken upper arm bone (humeral shaft fracture). Some of these patients also have weakness or paralysis in their hand and wrist due to injury to the radial nerve. The study compares patients with and without radial nerve problems to see if early ultrasound scans can accurately detect nerve damage before surgery.

All patients will receive standard care, including surgery to fix the fracture. Those with nerve problems will also have the nerve explored during surgery. The results of the ultrasound will be compared to what is found during the operation. Patients will be followed closely over 12 months to monitor nerve recovery, healing of the bone, and any complications.

The goal is to improve the early diagnosis and management of nerve injuries in arm fractures, using a safe, non-invasive ultrasound scan that could help guide treatment decisions.

Detailed Description

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Conditions

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Humerus Shaft Fracture Radial Nerve Palsy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Radial Nerve Palsy Group

Patients with humeral shaft facture and Radial Nerve Palsy

High-Resolution Ultrasound Evaluation of the Radial Nerve

Intervention Type DEVICE

High-resolution diagnostic ultrasound of the radial nerve is performed using a linear transducer (6-15 MHz) within 48 hours of admission in patients with humeral shaft fractures. The ultrasound systematically assesses the radial nerve's continuity, morphology, and relation to the fracture site. Based on established classification criteria (e.g., stretch neuropraxia, incarceration, partial/complete transection), the ultrasound findings guide intraoperative planning. All imaging is performed by board-certified musculoskeletal radiologists following a standardized protocol.

No radial Nerve Palsy

Patients with humeral shaft fracture but no radial nerve palsy

High-Resolution Ultrasound Evaluation of the Radial Nerve

Intervention Type DEVICE

High-resolution diagnostic ultrasound of the radial nerve is performed using a linear transducer (6-15 MHz) within 48 hours of admission in patients with humeral shaft fractures. The ultrasound systematically assesses the radial nerve's continuity, morphology, and relation to the fracture site. Based on established classification criteria (e.g., stretch neuropraxia, incarceration, partial/complete transection), the ultrasound findings guide intraoperative planning. All imaging is performed by board-certified musculoskeletal radiologists following a standardized protocol.

Interventions

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High-Resolution Ultrasound Evaluation of the Radial Nerve

High-resolution diagnostic ultrasound of the radial nerve is performed using a linear transducer (6-15 MHz) within 48 hours of admission in patients with humeral shaft fractures. The ultrasound systematically assesses the radial nerve's continuity, morphology, and relation to the fracture site. Based on established classification criteria (e.g., stretch neuropraxia, incarceration, partial/complete transection), the ultrasound findings guide intraoperative planning. All imaging is performed by board-certified musculoskeletal radiologists following a standardized protocol.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult patients aged 18 years or older.
* Diagnosed with traumatic humeral shaft fracture.
* Admitted and followed according to the local clinical protocol with a confirmed diagnosis.
* Underwent required investigations, including high-resolution ultrasonography and/or electromyography (EMG).
* Provided written informed consent to participate in the study.

Exclusion Criteria

* Pathological fractures due to malignancy or metabolic disorder.
* History of previous humeral fracture or pre-traumatic radial nerve deficit.
* Clinically detected vascular injury or major soft tissue loss accompanying the fracture.
* Incomplete diagnostic workup (absence of ultrasound or EMG examination).
* Declined participation or were lost to follow-up.
* Persons under 18 years of age.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istanbul Medeniyet University

OTHER

Sponsor Role lead

Responsible Party

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Mahmut Gumus

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Istanbul Medeniyet University

Istanbul, Kars, Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Mehmed Nuri Tutuncu, MD

Role: CONTACT

0090 531 265 33 79

Facility Contacts

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Tolga Onay, Associate Professor

Role: primary

00905054418123

Other Identifiers

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IstanbulMU_032025

Identifier Type: -

Identifier Source: org_study_id