Comfort and Vision With TOTAL30 Multifocal Lenses

NCT ID: NCT07284966

Last Updated: 2025-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

36 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-01-21

Study Completion Date

2027-01-21

Brief Summary

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This study is a single-arm, prospective, observational study conducted at one site to evaluate the comfort and vision of the TOTAL30 Multifocal (T30MF) contact lenses over the course of long wear days. The study will assess the proportion of positive subjective Visual Analog Scale (VAS) assessments of comfort and vision at 10, 12, 14, and 16 hours of wear on Days 1, 7, 14, and 30. Additionally, the study will explore subjective assessments of lens comfort using the CLDEQ-8 survey and measure logMAR visual acuity at both distance and near at Visit 1, Visit 2, and after 1 month of lens wear. Participants will undergo three site visits, with at-home surveys conducted at specified intervals to gather real-time data on comfort and vision.

Detailed Description

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Conditions

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Myopia Presbyopia Astigmatism

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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TOTAL30 Multifocal

TOTAL30 Multifocal

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Subjects are eligible for the study if they meet the following criteria:

* Subjects who currently wear soft multi-focal contact lenses and score \<12 on an entering CLDEQ-8 survey.
* Subjects who are \>= 40 years old.
* Subjects who can and are willing to wear their lenses for 13 hours per day during the study period, and 16 hours per day when questionnaires are being taken.
* Willing to insert their contact lenses between 6:00 am and 8:00 am on the days when questionnaires will be taken.
* Vision correctable in soft multi-focal contact lenses to 20/25 (0.10 log MAR) or better in each eye at 6M.
* Must be able to be successfully fit into the prescription parameters available for Total30 MF contact lenses.
* Required to have a smartphone and receive push notifications.
* Willing to attend all study visits.
* Willing to be diligent about answering the timed surveys in a prompt manner.

Exclusion Criteria

* Ocular anterior segment infection, inflammation, abnormality, or active disease that would contraindicate contact lens wear.
* Use of systemic or ocular medications for which contact lens wear could be contraindicated as determined by the investigator.
* Use of isotretinoin-derivatives.
* Use of lubricating drops.
* Monocular patients or patients fit with only 1 multifocal lens.
* Prior refractive surgery.
* History of herpetic keratitis, ocular surgery, or irregular cornea.
* Pregnant or lactating.
* Having participated in a clinical trial in the past 30 days.
* High-ADD habitual wearers using a different fitting approach than Alcon's multifocal fitting guide (e.g., J\&J or CooperVision's fitting guide adopting a modified monovision approach).
* Are past rigid CL wearers.
* Have a history of being diagnosed with dry eye or ocular allergies.
* Have history of severe ocular trauma.
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sengi

INDUSTRY

Sponsor Role collaborator

Scripps Poway Eyecare and Optometry

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jay Mashouf, OD

Role: PRINCIPAL_INVESTIGATOR

Scripps Optometric Group

Locations

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Scripps Optometric Group

San Diego, California, United States

Site Status

Countries

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United States

Central Contacts

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Amy Minshall

Role: CONTACT

858-530-2800

Facility Contacts

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Amy Minshall

Role: primary

858-530-2800

Other Identifiers

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JM-25-02

Identifier Type: -

Identifier Source: org_study_id