Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
PHASE2
5 participants
INTERVENTIONAL
2025-12-31
2026-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Fisetin
Fisetin
Fisetin 20mg/kg/day
Interventions
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Fisetin
Fisetin 20mg/kg/day
Eligibility Criteria
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Inclusion Criteria
* Moca score of 11 or higher
* Stable psychotropics and cognitive enhancing medications
Exclusion Criteria
* Presence of any medical condition, or abnormal routine blood test, that the investigator believes would put the subject at risk or would preclude the patient from completing all aspects of the trial
* Unstable medical disorders
* Ongoing treatment for active infection with antibiotics/antifungals
* Ongoing treatment for cancer
* Active alcohol or substance use disorder
* Recent active bleeding
* Patients taking oral anticoagulants, anti-cancer, anti-seizure medications, or other medications that could have a significant interaction with fisetin
* Use within the last month of other senolytic supplements, antioxidant supplements, natural health products
* Other neurologic or neurodegenerative conditions impacting cognition
* Active Major Depressive Episode, active suicidal thoughts or psychosis
* Any thing that would preclude the ability to undergo an MRI scan
60 Years
ALL
No
Sponsors
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Sunnybrook Research Institute
OTHER
Sunnybrook Health Sciences Centre
OTHER
Responsible Party
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Principal Investigators
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Krista Lanctôt, PhD
Role: PRINCIPAL_INVESTIGATOR
Sunnybrook Research Institute
Locations
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Sunnybrook Research Institute
Toronto, Ontario, Canada
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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6705
Identifier Type: -
Identifier Source: org_study_id
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