Analgesic Efficacy of SPSIP Block Versus Paravertebral Block Following Thoracotomy
NCT ID: NCT07275047
Last Updated: 2025-12-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
80 participants
INTERVENTIONAL
2025-12-15
2026-12-15
Brief Summary
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Detailed Description
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The serratus posterior superior intercostal plane block is a newer ultrasound-guided technique. In this method, local anesthetic is injected between the serratus posterior superior muscle and the intercostal muscles. Early studies suggest that it may provide wide pain relief, but its effectiveness specifically in thoracotomy patients has not yet been studied.
This randomized study aims to compare the pain-relieving effects of the serratus posterior superior intercostal plane block with those of the paravertebral block after thoracotomy. The goal is to find out whether this new block can be a safe and effective option for postoperative pain management.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Group SPSIP
Participants in this arm will receive an ultrasound-guided Serratus Posterior Superior Intercostal Plane Block. The block will be performed preoperatively with the patient in the appropriate position. A local anesthetic solution will be injected between the serratus posterior superior muscle and the intercostal muscles under real-time ultrasound guidance. The technique aims to achieve postoperative analgesia by providing sensory blockade across targeted thoracic dermatomes. No additional regional block will be performed in this group.
Serratus Posterior Superior Intercostal Plane Block
Ultrasound-guided regional anesthesia technique performed between the serratus posterior superior muscle and intercostal muscles.
Group Paravertebral
Participants in this arm will receive an ultrasound-guided thoracic paravertebral block. The block will be performed preoperatively with the patient in the appropriate position. Under real-time ultrasound guidance, a local anesthetic solution will be injected into the thoracic paravertebral space at the planned level to achieve unilateral somatic and sympathetic nerve blockade. This intervention is intended to provide postoperative analgesia following thoracotomy. No additional regional block will be administered in this group.
Thoracic Paravertebral Block
Ultrasound-guided injection of local anesthetic into the thoracic paravertebral space to provide unilateral analgesia.
Interventions
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Serratus Posterior Superior Intercostal Plane Block
Ultrasound-guided regional anesthesia technique performed between the serratus posterior superior muscle and intercostal muscles.
Thoracic Paravertebral Block
Ultrasound-guided injection of local anesthetic into the thoracic paravertebral space to provide unilateral analgesia.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* ASA physical status I-III according to the American Society of Anesthesiologists classification
* Able to understand the study procedures and provide written informed consent
Exclusion Criteria
* Allergy or hypersensitivity to local anesthetics or opioids
* Known or suspected coagulopathy
* Infection at the injection site
* History of thoracic surgery
* Severe cardiovascular disease
* Hepatic or renal failure
* Pregnant, suspected pregnancy, or breastfeeding
Significant neurological or psychiatric disorder that may interfere with study participatio
18 Years
65 Years
ALL
No
Sponsors
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Bursa City Hospital
OTHER_GOV
Responsible Party
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Mursel Ekinci
Assoc Prof
Locations
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Bursa City Hospital
Bursa, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Mustafa Dikici, MD
Role: primary
Role: backup
References
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Bayman EO, Brennan TJ. Incidence and severity of chronic pain at 3 and 6 months after thoracotomy: meta-analysis. J Pain. 2014 Sep;15(9):887-97. doi: 10.1016/j.jpain.2014.06.005. Epub 2014 Jun 23.
Wildgaard K, Ravn J, Kehlet H. Chronic post-thoracotomy pain: a critical review of pathogenic mechanisms and strategies for prevention. Eur J Cardiothorac Surg. 2009 Jul;36(1):170-80. doi: 10.1016/j.ejcts.2009.02.005.
Mehta S, Jen TTH, Hamilton DL. Regional analgesia for acute pain relief after open thoracotomy and video-assisted thoracoscopic surgery. BJA Educ. 2023 Aug;23(8):295-303. doi: 10.1016/j.bjae.2023.05.001. Epub 2023 Jun 22. No abstract available.
Tulgar S, Ciftci B, Ahiskalioglu A, Bilal B, Sakul BU, Korkmaz AO, Bozkurt NN, De Cassai A, Torres AJ, Elsharkawy H, Alici HA. Serratus Posterior Superior Intercostal Plane Block: A Technical Report on the Description of a Novel Periparavertebral Block for Thoracic Pain. Cureus. 2023 Feb 3;15(2):e34582. doi: 10.7759/cureus.34582. eCollection 2023 Feb.
Akin AN, Yildiz Y, Alver S, Ciftci B. Continuous serratus posterior superior intercostal plane block for postoperative analgesia management in the patient who underwent right atrial mass excision: a case report. BMC Anesthesiol. 2024 Apr 25;24(1):159. doi: 10.1186/s12871-024-02535-4.
Yildirim Y, Parlar Kilic S, Eyigor S, Eyigor C, Yildirim Y, Karaman E, Oyur Celik G, Uyar M. Validity and reliability of Turkish version of the Brief Pain Inventory-Short Form for patients with chronic nonmalignant pain. Agri. 2019 Nov;31(4):195-201. doi: 10.14744/agri.2019.25901.
Other Identifiers
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Bursa City Hospital 13
Identifier Type: -
Identifier Source: org_study_id