Efficacy and Safety of Home-based Structured Physical Exercise in Patients With Acute Ischemic Stroke
NCT ID: NCT07271082
Last Updated: 2025-12-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
208 participants
INTERVENTIONAL
2025-12-18
2026-09-01
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Exercise intervention group
Home-based structured physical exercise guidance.
Exercise intervention
Subjects will undergo 90 days of home-based structured physical exercise guidance.
Control group
Subjects will not receive structured physical exercise guidance but are encouraged to engage in regular physical exercise.
No interventions assigned to this group
Interventions
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Exercise intervention
Subjects will undergo 90 days of home-based structured physical exercise guidance.
Eligibility Criteria
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Inclusion Criteria
2. Acute ischemic stroke onset within 14 days;
3. modified Rankin scale (mRS) score ≤ 3;
4. Signed informed consent from the patients or the legally authorized representatives.
Exclusion Criteria
2. Concurrent osteoarthritis, fractures, deep vein thrombosis, unstable angina, severe heart diseases, respiratory diseases, or amputation that may theoretically make it difficult for participants to complete the physical exercise or ambulation;
3. Concurrent movement disorders such as Parkinson's disease or Parkinsonism;
4. Patients who have engaged in regular aerobic physical activity within the past 6 months, defined as more than 150 minutes of moderate-intensity aerobic physical activity; or more than 75 minutes of vigorous-intensity aerobic physical activity; or an equivalent combination of moderate- and vigorous-intensity activity throughout the week;
5. Unable to comply with the study procedures or follow-up due to psychiatric, cognitive, or emotional disorders;
6. Known pregnancy or lactation, or a positive pregnancy test;
7. Currently participating in another drug or device study;
8. Life expectancy less than 1 year;
9. Unable to communicate using a smartphone;
10. Other conditions considered by investigators to be unsuitable for inclusion.
18 Years
ALL
No
Sponsors
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Capital Medical University
OTHER
Responsible Party
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Ji Xunming,MD,PhD
Professor of Neurology, Xuanwu Hospital, Capital Medical University
Locations
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Taihe Hospital of Traditional Chinese Medicine
Fuyang, Anhui, China
Suzhou Municipal Hospital
Suzhou, Anhui, China
Beijing Pinggu District Hospital
Beijing, Beijing Municipality, China
Xihua County People's Hospital
Zhoukou, Henan, China
Shihezi People's Hospital
Shihezi, Xinjiang, China
Xuanwu Hospital, Capital Medical University, 100053
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Zongtao Liu
Role: primary
Zhengfei Ma
Role: primary
Yifei Chen
Role: primary
Chaoqun Li
Role: primary
Dekun Zhu
Role: primary
Chuanjie Wu, MD
Role: primary
Xunming Ji, MD
Role: backup
Other Identifiers
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HOPE-STROKE 2
Identifier Type: -
Identifier Source: org_study_id