BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation

NCT ID: NCT07256717

Last Updated: 2025-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

369 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-10

Study Completion Date

2026-02-25

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years. All participants receive supervised BPIT sessions (3-5 per week) progressing through five intensity lines defined by anatomical landmarks and ground reaction force:

Ground-Based (Low) Knee-Level (Low-Moderate) Standing (Moderate) Head-Level (Moderate-High) Plyometric (High-Impact)

The study aims to quantify improvements in functional movement efficiency, joint mobility, postural control, strength adaptation, and heart-rate variability while monitoring safety and individual overload indicators.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Primary Outcome Measures

Change in Functional Movement Screen (FMS) total score from baseline to Week 5 Change in Y-Balance Test reach distance (composite score) Timeframe: Baseline and Week 5

Secondary Outcome Measures

Change in 1-RM or estimated strength (squat, deadlift, overhead press) Change in resting HRV (RMSSD) Change in joint range of motion (goniometry) and postural sway Incidence of training-related discomfort or minor injury Timeframe: Baseline, weekly, and Week 5

Arms/Intervention Experimental: BPIT 5-Line Training Group Intervention: Behavioral: Balanced Progressive Intensity Training (BPIT) 5-Line Method Description: 5-week supervised progressive training using the BPIT 5-Line framework (ground-based → plyometric) Eligibility

Ages Eligible: 18 Years to 65 Years Sexes Eligible: All Accepts Healthy Volunteers: Yes

Inclusion Criteria

Healthy adults with regular exercise history Able to attend 3-5 training sessions/week Signed informed consent

Exclusion Criteria

Recent injury (\<3 months) Known cardiovascular, metabolic, or orthopaedic contraindications Pregnancy

Study Locations 13 Locations in India 2 Locations in USA, (Details of the location is uploaded on mmsxauthority.com webiste)

MMSx Authority , USA, GFFI Fitness Academy, New Delhi BodyGNTX USA BFS/AIHFT-approved facilities

Countries of Recruitment India U.S. FDA-regulated? No / No / No Human Subjects Protection Review Board Status Approved (or Submit for review if not yet) Board Name: Institutional Ethics Committee - MMSx Authority / GFFI Approval Number: BPIT-MULTI-2025-001 (or pending) Data Monitoring Committee No

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Physical Fitness

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Single-arm prospective interventional study

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

BPIT 5-Line Training Group

All participants receive the 5-week Balanced Progressive Intensity Training (BPIT) program using the 5-Line Principle (ground-based → knee-level → standing → head-level → plyometric) under supervised sessions 3-5 times per week.

Group Type EXPERIMENTAL

Balanced Progressive Intensity Training (BPIT) 5-Line Method

Intervention Type BEHAVIORAL

5-week supervised progressive training using the BPIT 5-Line framework developed by Dr. Neeraj Mehta.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Balanced Progressive Intensity Training (BPIT) 5-Line Method

5-week supervised progressive training using the BPIT 5-Line framework developed by Dr. Neeraj Mehta.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adults aged 18-65 years Generally healthy with regular physical activity history (at least 1-2 sessions per week for the past 3 months) Able to commit to 3-5 supervised training sessions per week for 5 weeks Willing and able to provide written informed consent Cleared by pre-screening (no acute injury, no contraindications)

Exclusion Criteria

* Acute musculoskeletal injury within the past 3 months Known cardiovascular, metabolic, or orthopaedic conditions that contraindicate exercise Pregnancy or planning pregnancy Use of medications or supplements that significantly affect muscle recovery or performance (e.g., corticosteroids, anabolic agents) Inability to follow the BPIT protocol or attend required sessions
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

BodyGNTX Fitness Institute

UNKNOWN

Sponsor Role collaborator

GFFI Fitness Academy

UNKNOWN

Sponsor Role collaborator

Indian Institute of Kinesiology and Biomechanics Science (IIKBS)

UNKNOWN

Sponsor Role collaborator

Bureau of Fitness Standards (BFS)

UNKNOWN

Sponsor Role collaborator

Active India Health & Fitness Trust (AIHFT)

UNKNOWN

Sponsor Role collaborator

Body Mechanic Chain of Gyms

UNKNOWN

Sponsor Role collaborator

Shri Mahaveer Ortho Clinic

UNKNOWN

Sponsor Role collaborator

Regain Fitness Zone

UNKNOWN

Sponsor Role collaborator

MMSx Authority Biomechanics Department

UNKNOWN

Sponsor Role collaborator

MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

BodyGNTX Fitness Institute

Columbus, Ohio, United States

Site Status RECRUITING

MMSx Authority Biomechanics Department

Powell, Ohio, United States

Site Status RECRUITING

MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER)

Powell, Ohio, United States

Site Status RECRUITING

Indian Institute of Kinesiology & Biomechanics Science (IIKBS)

Burhānpur, Madhya Pradesh, India

Site Status RECRUITING

Shri Mahaveer Ortho Clinic

Delhi, National Capital Territory of Delhi, India

Site Status RECRUITING

GFFI Fitness Academy

New Delhi, National Capital Territory of Delhi, India

Site Status RECRUITING

Active India Health & Fitness Trust (AIHFT)

New Delhi, National Capital Territory of Delhi, India

Site Status RECRUITING

Body Mechanics Gym P Ltd

New Delhi, National Capital Territory of Delhi, India

Site Status RECRUITING

Regain Fitness Zone

Greater Noida, Uttar Pardesh, India

Site Status RECRUITING

GFFI Fitness Academy

Agra, Uttar Pradesh, India

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States India

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Neeraj Mehta, Ph.D. (Biomechanics)

Role: primary

6148228038

Ashita Malhotra, GCP

Role: backup

6148228038

Tina Malhotra, MMSx Pro / CPT

Role: primary

6144775031

Sunita Malhotra, GCP

Role: backup

6144776065

Neeraj Mehta, Ph.D. (Biomechanics)

Role: primary

6148228038

Sunita Malhotra, GCP

Role: backup

6144776065

Dr. Anya Petrova, M.D., Ph.D. (Sports Med)

Role: primary

+919990744422

Laura Green, R.N.

Role: backup

+91-9990744422

Dr Karun Jain, MBBS, D'Ortho, MS Ortho

Role: primary

+91-8285257076

Karun Jain, MBBS

Role: backup

Sumit Khoney, MMSx Pro / CPT

Role: primary

08586836625

Pankaj Mehta, M.P.Ed.

Role: backup

+918447431421

Anupama Mahajan, Ph.D. (Maths)

Role: primary

+91-9873194695

Anupama Mahajan, PhD

Role: backup

+919873194695

Sunny Ghambir, CPT

Role: primary

9990960606

Gaurav Sharma, CPT, CSCS

Role: backup

9990960606

Chetan Sethi, MMSx Pro / CPT

Role: primary

+91-98998200922

Chetan Sethi, CPT, CSCS

Role: backup

+919899820922

Jeet Sharma, CPT

Role: primary

+91-9990744422

Gerik Mehta, CPT, CSCS

Role: backup

8586836625

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

MACREB-BPIT-2025-014

Identifier Type: OTHER

Identifier Source: secondary_id

BPIT-MULTI-2025-001

Identifier Type: -

Identifier Source: org_study_id