Generative AI-Based Simulation for Diagnostic Communication in Type 2 Diabetes (DIALOGUE-DM2)

NCT ID: NCT07252193

Last Updated: 2025-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-22

Study Completion Date

2025-12-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This randomized controlled trial evaluates the effectiveness of a generative artificial intelligence (AI)-based simulation program in improving diagnostic communication skills among medical students. The study is conducted at the Faculty of Higher Studies Iztacala, National Autonomous University of Mexico (UNAM).

A total of 120 medical students are randomized to either an intervention group using the DIALOGUE-DM2 AI simulation platform or a control group following traditional educational methods. Participants complete a pre-test, receive training according to group assignment, and then undergo a post-test evaluation.

The primary outcome is improvement in diagnostic communication skills, measured by standardized patient scenarios and validated rubrics. Secondary outcomes include self-reported confidence, communication domains, and inter-rater agreement between faculty evaluators and AI scoring.

This trial aims to provide high-quality evidence on the potential of generative AI to enhance communication training in medical education, specifically in the context of type 2 diabetes diagnosis.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study builds on a prior pilot trial (published in 2024) that demonstrated the feasibility of using generative artificial intelligence (AI) to train medical students in diagnostic communication. The current trial extends that work with a randomized, blinded, controlled design and a larger sample size.

Design:

The study is a randomized, blinded, parallel-group, controlled trial conducted at the Faculty of Higher Studies Iztacala (FES Iztacala), UNAM. A total of 120 medical students are enrolled and randomized (1:1) into either the intervention group (AI-based simulation training) or the control group (traditional training with standardized patients and faculty feedback).

Intervention:

* Intervention group: Students interact with the DIALOGUE-DM2 platform, which provides generative AI-driven simulated patients. They complete multiple diagnostic disclosure scenarios and receive immediate feedback on performance, based on standardized communication rubrics.
* Control group: Students receive standard training, including lectures and supervised practice with peer role-play and faculty-guided feedback.

Assessments:

* Pre-test: All students complete one standardized patient scenario with faculty and AI evaluation prior to intervention.
* Training phase: Participants complete their assigned training (AI vs. standard).
* Post-test: Students complete a standardized diagnostic disclosure scenario. Independent faculty evaluators (blinded to group assignment) and the AI platform score performance.

Outcomes:

* Primary outcome: Change in diagnostic communication performance score from pre-test to post-test, measured by validated rubrics (Kalamazoo framework, MRS).
* Secondary outcomes:
* Student self-assessment of communication confidence.
* Domain-specific improvements (information delivery, empathy, risk explanation, shared decision-making).
* Agreement between human evaluators and AI scoring.

Ethics and Oversight:

The study has been reviewed and approved by the Research Ethics Committee of FES Iztacala, UNAM (Approval Number CE/FESI/042025/1915). Risks are minimal, as the intervention is educational and non-invasive.

Significance:

This is the first randomized controlled trial in Mexico to evaluate a generative AI-based simulation for diagnostic communication. Results will inform the integration of AI-driven training tools into medical education curricula and could contribute to scalable innovations in the training of healthcare professionals for chronic disease management, starting with type 2 diabetes.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Type 2 Diabetes Mellitus Medical Education Diagnostic Communication Artificial Intelligence Simulation

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Generative AI Simulation-Based Education Medical Students Diagnostic Communication Skills Artificial Intelligence in Healthcare DIALOGUE-DM2

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Two-arm randomized, blinded, controlled trial comparing AI-based simulation training with traditional training in medical students facing type 2 diabetes disclosure scenarios.
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
Participant, Investigator, Outcomes Assessor

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

AI-Based Simulation Training (DIALOGUE-DM2)

Medical students assigned to this arm will receive training using the DIALOGUE-DM2 platform, which provides generative AI-driven simulated patients. Participants will engage in multiple diagnostic disclosure scenarios focused on type 2 diabetes and receive immediate feedback generated by the AI system. Feedback is aligned with validated communication frameworks (Kalamazoo, MRS). Training is conducted over several sessions prior to the post-test evaluation.

Group Type EXPERIMENTAL

AI-Based Simulation Training (DIALOGUE-DM2)

Intervention Type BEHAVIORAL

Medical students interact with the DIALOGUE-DM2 platform, a generative AI-based simulation system. The platform delivers virtual patient encounters focused on type 2 diabetes diagnostic disclosure. Students complete multiple simulated scenarios and receive immediate AI-generated feedback aligned with standardized communication rubrics (Kalamazoo, MRS). Training aims to enhance diagnostic communication skills prior to post-test evaluation.

Traditional Training

Medical students assigned to this arm will receive traditional communication skills training. This includes lectures, peer role-play, and faculty-supervised feedback sessions covering diagnostic disclosure in type 2 diabetes. Participants will complete the same number of training sessions as the intervention group before the post-test evaluation.

Group Type ACTIVE_COMPARATOR

Traditional Training

Intervention Type BEHAVIORAL

Medical students receive traditional training in diagnostic communication. This includes lectures, peer role-play, and faculty-supervised feedback sessions covering diagnostic disclosure in type 2 diabetes. The training duration and number of sessions are matched to the intervention group.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

AI-Based Simulation Training (DIALOGUE-DM2)

Medical students interact with the DIALOGUE-DM2 platform, a generative AI-based simulation system. The platform delivers virtual patient encounters focused on type 2 diabetes diagnostic disclosure. Students complete multiple simulated scenarios and receive immediate AI-generated feedback aligned with standardized communication rubrics (Kalamazoo, MRS). Training aims to enhance diagnostic communication skills prior to post-test evaluation.

Intervention Type BEHAVIORAL

Traditional Training

Medical students receive traditional training in diagnostic communication. This includes lectures, peer role-play, and faculty-supervised feedback sessions covering diagnostic disclosure in type 2 diabetes. The training duration and number of sessions are matched to the intervention group.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Medical students currently enrolled in the Faculty of Medicine (Medical Surgeon Program), UNAM-FES Iztacala.
* Age between 18 and 30 years.
* Able to provide informed consent.
* Willing to participate in all study phases (pre-test, intervention, post-test).

Exclusion Criteria

* Prior participation in the DIALOGUE pilot study.
* Previous formal training in diagnostic communication beyond the standard medical curriculum.
* Incomplete availability for scheduled sessions.
* Refusal or inability to provide informed consent.
Minimum Eligible Age

18 Years

Maximum Eligible Age

29 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Universidad Nacional Autonoma de Mexico

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Héctor Iván Saldívar Cerón

Principal Investigator, FES Iztacala, UNAM

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Universidad Nacional Autónoma de México, Faculty of Higher Studies Iztacala (FES Iztacala)

Tlalnepantla, , Mexico

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Mexico

References

Explore related publications, articles, or registry entries linked to this study.

Suarez-Garcia RX, Chavez-Castaneda Q, Orrico-Perez R, Valencia-Marin S, Castaneda-Ramirez AE, Quinones-Lara E, Ramos-Cortes CA, Gaytan-Gomez AM, Cortes-Rodriguez J, Jarquin-Ramirez J, Aguilar-Marchand NG, Valdes-Hernandez G, Campos-Martinez TE, Vilches-Flores A, Leon-Cabrera S, Mendez-Cruz AR, Jay-Jimenez BO, Saldivar-Ceron HI. DIALOGUE: A Generative AI-Based Pre-Post Simulation Study to Enhance Diagnostic Communication in Medical Students Through Virtual Type 2 Diabetes Scenarios. Eur J Investig Health Psychol Educ. 2025 Aug 7;15(8):152. doi: 10.3390/ejihpe15080152.

Reference Type BACKGROUND
PMID: 40863274 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

UNAM-DIALOGUE-DM2-2025

Identifier Type: -

Identifier Source: org_study_id