Modified Nuclear Phacoemulsification in Brown Cataract

NCT ID: NCT07252154

Last Updated: 2025-11-26

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-03-01
• Study Completion Date: 2025-11-01

Brief Summary

Irrigation of the nucleus with saline for 30 seconds after creating the central groove.

Detailed Description

The hard nucleus is physiologically immune against water flow from out to inside the nucleus but we discovered that it is not immune against the flow of water from inside the nucleus to outside. So, we are doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer.

. As we know, the nucleus of the lens has the highest concentration of crystalline (high osmotic pressure), so the water will flow from the center of the nucleus to the outer surface without any resistance, and all adhesions and bonds between lens fibers will be broken at once, and the nucleus becomes softer.

Conditions

Brown Cataract

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Brown cataract

doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer

Group Type: EXPERIMENTAL

phacoemulsification

Intervention Type: PROCEDURE

doing phacoemulsification as usual but we stop when the gutter becomes half the thickness of the nucleus then we use tip of the phaco as irrigation for 30 seconds. the nucleus will become more softer

Interventions

phacoemulsification

doing phacoemulsification as usual but we stop when the gutter becomes half the thickness of the nucleus then we use tip of the phaco as irrigation for 30 seconds. the nucleus will become more softer

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Brown cataract

Exclusion Criteria

• white cataract
• soft cataract

• Minimum Eligible Age: 50 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Hassan Lotfy Fahmy

Prof

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Assiut univercity

Asyut, , Egypt

Countries

Egypt

Other Identifiers

17209067

Identifier Type: -

Identifier Source: org_study_id