Efficacy and Safety of Etrasimod in Elderly Patients With Ulcerative Colitis

NCT ID: NCT07243639

Last Updated: 2025-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-01

Study Completion Date

2026-09-30

Brief Summary

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Eligible patients will be identified in regular clinical practice. After providing thorough explanation and obtaining voluntary written informed consent, the clinical course, adverse events, endoscopic findings, and histopathological changes in biopsy specimens after Etrasimod administration will be prospectively collected and analyzed.

Detailed Description

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Conditions

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Ulcerative Colitis (Disorder)

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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elderly patients (aged 65 years or older) with active ulcerative colitis

Group Type EXPERIMENTAL

Etrasimod administration

Intervention Type DRUG

2 mg of Etrasimod is orally administered everyday.

Interventions

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Etrasimod administration

2 mg of Etrasimod is orally administered everyday.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with active ulcerative colitis

Exclusion Criteria

* the presence of acute or chronic renal failure, chronic heart disease, pulmonary infection, liver cirrhosis, colorectal cancer, autoimmune disease, and infectious disease
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Showa Inan General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Akira Horiuchi

Chief of Digestive Disease Center

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Showa Inan General Hospital

Komagane, Nagano, Japan

Site Status RECRUITING

Countries

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Japan

Central Contacts

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Norio Saegusa

Role: CONTACT

81265822121 ext. 2090

Other Identifiers

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Etrasimod in elderly UC

Identifier Type: -

Identifier Source: org_study_id

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