Evaluating Atherosclerotic Disease Progression in Patients With Diabetes Mellitus
NCT ID: NCT07237685
Last Updated: 2025-11-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
1000 participants
OBSERVATIONAL
2025-06-06
2036-10-01
Brief Summary
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This study will follow people with type 2 diabetes who have already had a special heart scan called a coronary CT angiography. This scan takes detailed pictures of the heart's blood vessels.
The goal is to understand how heart disease changes over time in people with type 2 diabetes, by looking at repeat scans and other health information. By learning more about how plaque builds up or gets worse, researchers hope to find better ways to identify which patients are most at risk for future heart problems.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Previous completion of CCTA scan for CAD assessment
* Diagnosed with Type 2 Diabetes and currently receiving glucose lowering treatment
* Sufficient image quality of the CCTA scan (at least 2/3 vessels of sufficient quality for assessment).
Exclusion Criteria
* Presence of an unstable condition
* Ingeligibility for CCTA acquisition due to severe renal dysfunction (eGFR ≤ 30 mL/min/1.73m²) or known hypersensitivity or contraindication to CT contrast agents
* Any other treatment or clinically relevant condition that could interfere with the conduct or interpretation of the study in the opinion of the investigator
* inability or unwillingness to comply with the protocol requirements, or deemed by investigator to be unfit for the study
* Baseline (routine care) CCTA performed \< 2 years or \> 5 years before inclusion
18 Years
ALL
No
Sponsors
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Horizon Innovative Health Initiative
UNKNOWN
Novo Nordisk A/S
INDUSTRY
INSTITUTO DE INVESTIGACION BIOMEDICA DE SALAMANCA (IBSAL)
UNKNOWN
Cardiology Centers of the Netherlands
UNKNOWN
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OTHER
Responsible Party
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M.M. Winter
Principal Investigator
Locations
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Amsterdam University Medical Centers
Amsterdam, , Netherlands
Cardiology Centers of the Netherlands
Amsterdam, , Netherlands
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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NL86138.018.24
Identifier Type: -
Identifier Source: org_study_id
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