A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

NCT ID: NCT07225309

Last Updated: 2025-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-30

Study Completion Date

2029-04-13

Brief Summary

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The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to learn what participants and providers think about the therapy, including how the therapy is designed, outside factors, available resources, and how the people involved affect how well MCP-L works.

Detailed Description

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Conditions

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Breast Cancer Prostate Cancer Colorectal Cancer Thyroid Cancer Breast Cancer Stage III Breast Cancer Stage IV Prostate Cancer Stage III Prostate Cancer Stage IV Colorectal Cancer Stage III Colorectal Cancer Stage IV Thyroid Cancer Stage III Thyroid Cancer Stage IV

Keywords

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Breast cancer Breast cancer Stage III Breast cancer Stage IV Prostate cancer Prostate cancer Stage III Prostate cancer Stage IV Colorectal cancer Colorectal cancer Stage III Colorectal cancer Stage IV Thyroid cancer Thyroid cancer Stage III Thyroid cancer Stage IV 25-240 Memorial Sloan Kettering Cancer Center

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Experimental Intervention

Meaning-Centered Psychotherapy for Latinos (MCP-L)

Group Type EXPERIMENTAL

Meaning-Centered Psychotherapy for Latinos /MCP-L

Intervention Type BEHAVIORAL

MCP-L is a structured 7-session manualized intervention culturally adapted into Spanish for Latino participants diagnosed with advanced cancer, which utilizes a mixture of didactics, discussion and experiential exercises that focus on particular themes related to meaning and advanced cancer. It is 60-minute individual sessions delivered every week or intermittently (depending on participant preference) for up to approximately 3 months (in this time period) in the event of medical illness.

Control Intervention

Cognitive Behavioral Therapy (CBT)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Meaning-Centered Psychotherapy for Latinos /MCP-L

MCP-L is a structured 7-session manualized intervention culturally adapted into Spanish for Latino participants diagnosed with advanced cancer, which utilizes a mixture of didactics, discussion and experiential exercises that focus on particular themes related to meaning and advanced cancer. It is 60-minute individual sessions delivered every week or intermittently (depending on participant preference) for up to approximately 3 months (in this time period) in the event of medical illness.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

EMR Criteria

\- Documentation of Disease

* Pathologically confirmed breast, prostate, colorectal, or thyroid solid tumor cancer (either most recent or new diagnosis)

* Definition of Disease \[or Measurable Disease\]
* Diagnosed with stages III or IV

* Prior Treatment
* Receiving ambulatory care at INCan

Self-Report Criteria

* Age ≥ 18 years
* Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
* Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
* Providing care (or services) to Mexican cancer patients at INCan
* Has access to internet and an electronic device
* Agrees to be audio-recorded


* Age ≥ 18 years
* Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
* Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
* Providing care (or services) to Mexican cancer patients at INCan
* Has access to internet and an electronic device
* Agrees to be audio-recorded

Exclusion Criteria

EMR Criteria

* Prior Treatment

* In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation
* Diagnosed with a major disabling and serious psychiatric condition

Self-Report Criteria

* Presence of suicide risk determined by the Columbia-Suicide Severity Rating Scale
* Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"

Provider Eligibility Criteria:
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Memorial Sloan Kettering Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rosario Costas Muniz, PhD

Role: PRINCIPAL_INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Locations

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Memorial Sloan Kettering Cancer Center

New York, New York, United States

Site Status

Countries

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United States

Central Contacts

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Rosario Costas Muniz, PhD

Role: CONTACT

Phone: 646-888-8062

Email: [email protected]

Francesca Gany, MD, MS

Role: CONTACT

Phone: 646-888-8054

Email: [email protected]

Related Links

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http://www.mskcc.org

Memorial Sloan Kettering Cancer Center

Other Identifiers

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25-240

Identifier Type: -

Identifier Source: org_study_id