Evaluation of TL-925 for the Treatment of Seasonal Allergic Conjunctivitis
NCT ID: NCT07220408
Last Updated: 2025-11-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE2
60 participants
INTERVENTIONAL
2025-10-23
2026-02-28
Brief Summary
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The study comprises of a screening and treatment period using the conjunctival allergen challenge model to evaluate TL-925 for the treatment of allergic conjunctivitis.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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TL-925 Arm
Subjects will be dosed in clinic.
TL-925
TL-925 is an eye drop.
Placebo Arm
Subjects wil be dosed in clinic.
Placebo
The composition of the placebo is identical to the active formulation except for the exclusion of the active ingredient.
Interventions
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TL-925
TL-925 is an eye drop.
Placebo
The composition of the placebo is identical to the active formulation except for the exclusion of the active ingredient.
Eligibility Criteria
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Inclusion Criteria
* Female subjects of childbearing potential and their male partners must both use a highly effective contraception method during the study.
* Documented history of ocular allergies and a positive skin test reaction to a seasonal (grass, ragweed, tree pollen) or perennial (cat dander, dog dander, dust mites, cockroach) allergen as confirmed by an allergic skin test conducted at Visit 1 or within the past 60 months.
* Calculated best-corrected visual activity
* Positive bilateral CAC reaction
Exclusion Criteria
* Any ocular surgical intervention within the last 3 months OR refractive surgery within the last 6 months
* Any ongoing ocular infection (bacterial, viral or fungal)
18 Years
ALL
No
Sponsors
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Telios Pharma, Inc.
INDUSTRY
Responsible Party
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Locations
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Advancing Vision Research
Smyrna, Tennessee, United States
Countries
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Central Contacts
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Other Identifiers
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TL-925-314
Identifier Type: -
Identifier Source: org_study_id
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