Radicle Clarity RPN: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes.
NCT ID: NCT07219641
Last Updated: 2025-11-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
750 participants
INTERVENTIONAL
2025-11-05
2027-01-11
Brief Summary
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Detailed Description
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Eligible participants will (1) have the opportunity for meaningful improvement (at least 30%) in their primary health outcome and (2) express acceptance in taking a product and not knowing its formulation until the end of the study.
Participants that report a known cardiac dysfunction, liver or kidney disease may be excluded. Participants that report a known contraindication or with well-established, significant safety concerns due to illness will be excluded. Heavy drinkers and those who report they are pregnant, trying to become pregnant, or breastfeeding will be excluded. Participants that report taking medications with a known contraindication or with well-established, significant safety concerns will be excluded.
Self-reported data are collected electronically from eligible participants for 7 weeks. Participant reports of health indicators will be collected at baseline, throughout the active period of study product use, and in a final survey. All study assessments will be electronic; there are no in-person visits or assessments for this real-world.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
DOUBLE
Study Groups
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Placebo Control
Clarity Product Placebo Control
Clarity Product Placebo Control
Participants will use their Clarity Product Placebo Control as directed for a period of 6 weeks.
Active Product 1
Clarity Active Product 1
Clarity Active Product 1
Participants will use their Clarity Active Product 1 as directed for a period of 6 weeks.
Active Product 2
Clarity Active Product 2
Clarity Active Product 2
Participants will use their Clarity Active Product 2 as directed for a period of 6 weeks.
Interventions
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Clarity Product Placebo Control
Participants will use their Clarity Product Placebo Control as directed for a period of 6 weeks.
Clarity Active Product 1
Participants will use their Clarity Active Product 1 as directed for a period of 6 weeks.
Clarity Active Product 2
Participants will use their Clarity Active Product 2 as directed for a period of 6 weeks.
Eligibility Criteria
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Inclusion Criteria
* Adults, at least 21 years of age at the time of electronic consent, inclusive of all ethnicities, races, and gender identities.
* Assigned sex at birth will determine sex-specific recruitment and surveys (male vs female) employed, when needed.
* Resides in the United States.
* Has the opportunity for at least 30% improvement in their primary health outcome.
* Expresses a willingness to take a study product and not know the product identity (active or placebo) until the end of the study.
* Exclusion
Individuals who report any of the following during screening will be excluded from participation:
* Report being pregnant, trying to become pregnant, or breastfeeding.
* Unable to provide a valid US shipping address and mobile phone number.
* Reports current enrollment in another clinical trial.
* Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day).
* Unable to read and understand English.
* Reports a current and/or recent (up to 3 months ago) major illness and/or surgery that poses a known, significant safety risk.
* Reports a diagnosis of cardiac dysfunction, liver or kidney disease that presents a known contraindication and/or a significant safety risk with any of the study product ingredients.
* NYHA Class III or IV congestive heart failure, atrial fibrillation, uncontrolled arrhythmias, cirrhosis, end-stage liver disease, stage 3b or 4 chronic kidney disease, or kidney failure.
* Reports taking medications that have a well-established moderate or severe interaction, posing a substantial safety risk with any of the study product ingredients.
* Anticoagulants, antihypertensives, anxiolytics, antidepressants, chemotherapy, immunotherapy, sedative hypnotics, seizure medications, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, diabetic medications, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOIs, or thyroid products.
* Reports current use of the primary ingredient(s) and/or similar product(s) to the active study product(s) that may limit the effects of the study products.
* Lack of reliable daily access to the internet.
21 Years
105 Years
ALL
Yes
Sponsors
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Radicle Science
INDUSTRY
Responsible Party
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Principal Investigators
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Susan Hewlings
Role: PRINCIPAL_INVESTIGATOR
Radicle Science
Locations
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Radicle Science Inc.
Del Mar, California, United States
Countries
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Central Contacts
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Facility Contacts
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Study Manager
Role: primary
Megan Mosely
Role: backup
Related Links
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Related Info
Other Identifiers
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RADX_P_2406_RPN
Identifier Type: -
Identifier Source: org_study_id