Comparison of Methods for Assessing Intraocular Lens Position

NCT ID: NCT07218419

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

55 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-11-03

Study Completion Date

2026-01-14

Brief Summary

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Prospective, multi-center, non-interventional, open label, clinical study.

Detailed Description

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The objective is to evaluate two methods for assessing IOL tilt and decentration in patients who have been unilaterally or bilaterally implanted with a refractive or diffractive nontoric TECNIS IOL before participating into this study. The agreement will be assessed between the decentration measurements derived from retro-illuminated slit lamp image analysis and those obtained from the subjective slit lamp grading method.

Conditions

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Tilt and Decentration

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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IOL Decentration

The objective is to evaluate two methods for assessing IOL tilt and decentration in patients who have been unilaterally or bilaterally implanted with a refractive or diffractive non- toric TECNIS IOL before participating into this study. The agreement will be assessed between the decentration measurements derived from retro-illuminated slit lamp image analysis and those obtained from the subjective slit lamp grading method.

IOL Decentration Assessment

Intervention Type DIAGNOSTIC_TEST

This study assesses two methods to measure IOL decentration. Each subject will be evaluated in only one eye with both methods for assessing IOL decentration:

(i) retro-illuminated slit lamp image analysis (objective slit lamp method) and (ii) subjective slit lamp grading method. There is no treatment or intervention on this study.

Interventions

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IOL Decentration Assessment

This study assesses two methods to measure IOL decentration. Each subject will be evaluated in only one eye with both methods for assessing IOL decentration:

(i) retro-illuminated slit lamp image analysis (objective slit lamp method) and (ii) subjective slit lamp grading method. There is no treatment or intervention on this study.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Basic Science

Eligibility Criteria

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Inclusion Criteria

All criteria apply to study eye.

The subject must:

* Read, understand, and sign the informed consent and HIPAA authorization forms, and receive a fully executed copy of the signed forms.
* Appear capable and willing to adhere to the clinical protocol procedures.
* Be 22 years of age or older at the time of screening.
* Have undergone unilateral or bilateral implantation with a desired TECNIS non-toric IOL design (e.g., refractive or diffractive).
* Be at least three months postoperative in the study eye.

Exclusion:

All criteria apply to study eye.

The subject must NOT:

* Any medical or ocular history, in the opinion of the investigator, that may impact study procedures such as ocular trauma, pseudoexfoliation syndrome, retinal pigment degeneration, macular pathology, glaucoma, retinal disease, corneal disease, or corneal opacities.
* Have any condition that may affect the eye's ability to fixate (e.g., amblyopia).
* Have a history of corneal or intraocular surgery other than cataract surgery.
* Be using ocular or systemic medications known to interact with dilation drops.
* Have a history of hypersensitivity, allergic reaction or other contraindication to dilation drops.
* Have clinically significant pupil abnormalities (e.g., non-reactive, fixed, or abnormally shaped pupils).
* Have an intraocular pressure of ≥ 21mm Hg before mydriasis.
* Have a mydriatic pupil diameter of less than 6mm.
* Have participated in clinical trial within 7 days prior to study enrollment.
* Be an employee (e.g., Investigator, Coordinator, or Technician) or immediate family member (including partner, child, parent, grandparent, grandchild, or sibling) of an employee of the clinical site or study sponsor.
* Be currently pregnant or lactating.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Johnson & Johnson Surgical Vision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Surgical Vision Inc. Johnson and Johnson

Role: STUDY_DIRECTOR

Study Director

Locations

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Empire Eye & Laser Center

Bakersfield, California, United States

Site Status NOT_YET_RECRUITING

Jones Eye Center

Sioux City, Iowa, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Siddhesh Raorane

Role: CONTACT

Phone: 904-539-7205

Email: [email protected]

Kristen Leraas

Role: CONTACT

Email: [email protected]

Other Identifiers

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MDEV109TDMD

Identifier Type: -

Identifier Source: org_study_id