Effect of Extracorporeal Shockwave Therapy on Pruritus in Neurodermatitis Patients

NCT ID: NCT07206680

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-15

Study Completion Date

2025-10-25

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to evaluate the therapeutic effect of shockwave therapy on reducing pruritus in neurodermatitis patients.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Based on the occurrence of side effects caused by conventional medication for prolonged employment, dermatologists and patients show solicitude for multifaceted effective methods to control the chronic and relapsing nature of neurodermatitis.

Although new modalities are continuously coming up for pruritus, there remains a great gap for providing symptom relief.

Furthermore, there is a lack in the quantitative knowledge and information in the published studies about benefits of shockwave therapy on the treatment of pruritus in neurodermatitis patients. So, this study is designed to outline the therapeutic efficacy of shockwave therapy on the treatment of pruritus in neurodermatitis patients.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Neurodermatitis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Shockwave therapy + corticosteroids + emollients

It will include 17 patients suffering from neurodermatitis who will receive shockwave therapy for 10min, 4 sessions, once per week and emollients \& corticosteroids for a month.

Group Type EXPERIMENTAL

Shockwave therapy

Intervention Type DEVICE

The procedures for Extracorporeal Shockwave Therapy (ESWT) involve several steps. First, the patient is positioned comfortably, and the physiotherapist explains the treatment procedure. Before the session begins, the device cables are checked for proper functioning. The shockwave type used is Non-Focused/Radial, with a treatment duration not exceeding 10 minutes. The frequency is set at 4 Hz, and the intensity ranges from 0.05 to 0.20 mJ/mm². Each session involves a total of 1000 to 2000 shocks. The treatment consists of four sessions, each held once a week.

Emollients & corticosteroids

Intervention Type DRUG

Patients in both groups will receive emollients \& corticosteroids for one month.

Corticosteroids & Emollients

It will include 17 patients suffering from neurodermatitis who will receive their emollients \& corticosteroids only for a month.

Group Type ACTIVE_COMPARATOR

Emollients & corticosteroids

Intervention Type DRUG

Patients in both groups will receive emollients \& corticosteroids for one month.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Shockwave therapy

The procedures for Extracorporeal Shockwave Therapy (ESWT) involve several steps. First, the patient is positioned comfortably, and the physiotherapist explains the treatment procedure. Before the session begins, the device cables are checked for proper functioning. The shockwave type used is Non-Focused/Radial, with a treatment duration not exceeding 10 minutes. The frequency is set at 4 Hz, and the intensity ranges from 0.05 to 0.20 mJ/mm². Each session involves a total of 1000 to 2000 shocks. The treatment consists of four sessions, each held once a week.

Intervention Type DEVICE

Emollients & corticosteroids

Patients in both groups will receive emollients \& corticosteroids for one month.

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age range between 55:75 years.
* Male and female patients will participate in the study.
* All patients have neurodermatitis.
* All patients will be received the same approach of medication and nursing care.
* All patients enrolled in the study will have their informed consent.

Exclusion Criteria

* Patients diagnosed with cancer.
* Pregnant woman.
* active infection.
* Patients with any systemic diseases that may interfere with the objectives of the study.
* Cardiac pacemakers or other implantable devices.
* Current anticoagulation use.
* Any other cause of itching
Minimum Eligible Age

55 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Cairo University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Abd Al Rahman Khaled Muhammed Muhammed

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Nessrien Afify Abd El Rashid, PhD

Role: STUDY_CHAIR

Assistant Professor, Cairo University

Noha Zakaria Tawfik, PhD

Role: STUDY_DIRECTOR

Assistant Professor, Suez Canal University

Doaa Atef Aly, PhD

Role: STUDY_DIRECTOR

Lecturer, Cairo university

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Suez Canal University Hospital

Ismailia, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

P.T.REC/012/005978

Identifier Type: -

Identifier Source: org_study_id