COVID-Related Tinnitus Timeline

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

233 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-01

Study Completion Date

2025-08-01

Brief Summary

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COVID-19 is a respiratory disease caused by the coronavirus SARS-CoV-2, for which the first cases were reported in China, by December 2019. Previous studies reported cases of tinnitus following COVID infection, most of them mild and with similar characteristics to other forms of tinnitus. Our aim is to further explore the relationship between COVID-19 and tinnitus. For this purpose we analyzed people in the city of Volta Redonda, Brazil after a COVID-19 infection. In detail we compared those with new onset tinnitus during or after COVID-19 with those without tinnitus and those with tinnitus onset before the COVID-19 infection. Moreover we analyzed the prevalence of post-COVID tinnitus along the pandemic timeline, from 2020 to 2024.

Detailed Description

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Two-hundred and thirty three patients over 18 years old and previously diagnosed with COVID-19 confirmed by either a RT-PCR, antibodies or antigens test were included. Patients were subdivided in three groups: no tinnitus (NT), tinnitus that already existed before COVID-19 (chronic tinnitus, CT) and tinnitus that arose during or after COVID-19 (post-COVID-19 tinnitus, PCT). Data concerning COVID-19 symptoms, drugs prescribed for COVID-19, tinnitus characteristics, comorbidities and other otological symptoms were collected. Tinnitus assessment included pure tone audiograms, the Tinnitus Handicap Inventory (THI), visual-analog scales (VAS) for loudness and distress as well as the hospital anxiety and depression scale (HADS). Patients with CT were additionally asked whether their tinnitus worsened after their COVID-19 infection.

Conditions

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Hearing Disorders COVID-19 Pandemic

Keywords

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covid-19 tinnitus

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* previous COVID-19 infection

Exclusion Criteria

* \< 18 yo
* not willing to give informed consent

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Ricardo Rodrigues Figueiredo

MD,MSc,PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Norma O Penido, MD,PhD

Role: STUDY_CHAIR

Universidade Federal de São Paulo

Locations

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OTOSUL, Otorrinolaringologia Sul-Fluminense

Volta Redonda, Rio de Janeiro, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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TinCOVID

Identifier Type: -

Identifier Source: org_study_id