Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids

NCT ID: NCT07199673

Last Updated: 2025-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

128 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-07

Study Completion Date

2026-01-06

Brief Summary

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Objective of this study is to compare the outcome of Injection Sclerotherapy versus Rubber Band Ligation for second degree hemorrhoids in terms of bleeding and efficacy.

Detailed Description

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There is a difference in the outcome of Injection Sclerotherapy versus Rubber Band Ligation for second degree hemorrhoids in terms of bleeding and efficacy.

Conditions

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Hemorrhoid

Keywords

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Injection Sclerotherapy Rubber Band Ligation Second Degree Hemorrhoids

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Group IST

5% phenol in almond oil

Group Type OTHER

Injection Sclerotherapy

Intervention Type DRUG

identifying the hemorrhoidal pedicle, 3-5 ml of 5% phenol in almond oil is injected into the submucosal plane of the hemorrhoid pedicle

Group RBL

rubber band is applied at the base of each hemorrhoid using Barron's Gun and Elise's tissue forceps.

Group Type OTHER

Rubber Band Ligation

Intervention Type DEVICE

knee-elbow position is used. After identifying the hemorrhoids with a proctoscope, a rubber band is applied at the base of each hemorrhoid using Barron's Gun and Elise's tissue forceps.

Interventions

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Injection Sclerotherapy

identifying the hemorrhoidal pedicle, 3-5 ml of 5% phenol in almond oil is injected into the submucosal plane of the hemorrhoid pedicle

Intervention Type DRUG

Rubber Band Ligation

knee-elbow position is used. After identifying the hemorrhoids with a proctoscope, a rubber band is applied at the base of each hemorrhoid using Barron's Gun and Elise's tissue forceps.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adults aged between 18 and 75 who have been diagnosed with second-degree hemorrhoids

Exclusion Criteria

* Patients with thrombosed hemorrhoids, and those with serious comorbid conditions such as heart, kidney, or liver diseases, coagulation disorders, or severe anemia.

* Individuals who have received treatment for hemorrhoids in the past six months.
* Pregnant women.
* Patients unable to commit to necessary follow-up appointments.
* Patients with a history or current presence of colorectal cancer or anal malignancy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gulab Devi Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mudassar Malik

Post Graduation Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Gulab devi Hospital Lahore

Lahore, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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AAMC/IRB/EA252025

Identifier Type: -

Identifier Source: org_study_id