CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad

NCT ID: NCT07197151

Last Updated: 2025-09-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-08-01

Study Completion Date

2025-09-01

Brief Summary

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Collect some tumor tissue specimens from patients who have undergone colorectal cancer surgery and conduct experiments such as immunohistochemistry to observe the expression of related genes in colorectal cancer.

Detailed Description

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We need to collect postoperative specimens and adjacent normal tissue specimens from patients with colorectal cancer for immunohistochemical staining. There is no need to conduct any other grouping of the patients.

Conditions

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Colorectal Cancer (CRC) Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Interventions

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Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens

Perform surgery on patients with colorectal cancer and collect cancer and adjacent tissue specimens

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Inclusion Criteria:(1) Patients diagnosed with colorectal cancer who received surgical treatment and postoperative chemotherapy (2) Patients who were conscious of their condition and voluntarily participated (3) No other serious underlying diseases

Exclusion Criteria:(1) Concurrent other serious chronic diseases or organ damage (2) Diagnosed with benign colorectal tumors
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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hui hou

OTHER

Sponsor Role lead

Responsible Party

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hui hou

Chief Physician

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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The Second Affiliated Hospital of Anhui Medical University

Hefei, Anhui, China

Site Status

Countries

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China

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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2022zhyx-C39

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

280211

Identifier Type: -

Identifier Source: org_study_id

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