Trastuzumab Deruxtecan in Advanced Breast Cancer

NCT ID: NCT07180264

Last Updated: 2025-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

118 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-28

Study Completion Date

2029-02-28

Brief Summary

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To evaluate the efficacy and safety of trastuzumab deruxtecan in advanced breast cancer patients.

Detailed Description

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Conditions

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Advanced Breast Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Trastuzumab deruxtecan

Trastuzumab deruxtecan, recommended dose 5.4mg/kg, every 21 days

Trastuzumab deruxtecan

Intervention Type DRUG

Trastuzumab deruxtecan is a combination of the targeted cancer drug trastuzumab (also known as Herceptin) and a chemotherapy drug called deruxtecan or DXd.

Interventions

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Trastuzumab deruxtecan

Trastuzumab deruxtecan is a combination of the targeted cancer drug trastuzumab (also known as Herceptin) and a chemotherapy drug called deruxtecan or DXd.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Aged ≥18 and older
* Breast cancer patients meeting current guideline recommendations and planning to receive trastuzumab deruxtecan
* ECOG 0-1

Exclusion Criteria

* During pregnancy and lactation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wenjin Yin

OTHER

Sponsor Role lead

Responsible Party

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Wenjin Yin

Deputy Chief of Breast Surgery Department

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Wenjin Yin, M.D.

Role: PRINCIPAL_INVESTIGATOR

Renji Hospital,School of Medicine, Shanghai Jiaotong University

Locations

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Renji Hospital, School of Medicine, Shanghai Jiaotong University

Shanghai, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Wenjin Yin, M.D.

Role: CONTACT

86(21)68385569

Facility Contacts

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Wenjin Yin

Role: primary

86(21)68385569

Other Identifiers

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LY2025-137-B

Identifier Type: -

Identifier Source: org_study_id

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