Comparing Relative Strengths of Statistical Associations Between Psychological Traits and Vaccination-Related Outcomes I

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1786 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-12-30

Study Completion Date

2025-02-27

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this study was to identify psychological motives that had the strongest statistical associations with vaccine outcomes in order to identify novel intervention targets to be used in vaccine promotion efforts. A national sample of US adults completed an online survey containing a variety of vaccine-related measures and psychological trait measures.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Testing a Personalized Normative Feedback Intervention for Vaccine Hesitancy

NCT05787015

COVID-19 Vaccine Hesitancy

UNKNOWN NA

Anxiety, Mood, and Health Behaviors in Young Adults

NCT03128437

Anxiety Sensitivity

COMPLETED NA

Cerebrovascular Health and Resilience in Midlife

NCT06029348

Psychological Stress Cardiovascular Diseases Cerebrovascular Disorders

RECRUITING NA

MVP RCT: Mind and Voice Project Randomized Control Trial

NCT04018807

Physical Health Mental Health Alcohol; Use, Problem +1 more

COMPLETED NA

Psychological and Lifestyle Factors on Health Outcomes

NCT04780867

Psychological Stress Immune Health +3 more

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A national sample of US adults were recruited through Dynata, an online survey panel company, to complete an online survey. Participants completed a variety of vaccine-related survey items and an unprecedented number (\>20) of psychological trait measures. This was possible by using a Planned Missingness Design, where respondents only answer a predetermined subset of survey questions, which allows us to include more measures without significantly increasing the burden for participants.

Participants were randomized to one of the three question blocks, where each block had a predetermined set of items that were roughly 1/3 of the items from each psychological trait measure. They were also randomized to complete questions that were about the psychological traits in general or about vaccines specifically.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Vaccination Vaccination Hesitancy Vaccination Promotion Psychological Aspects

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Decades of research has shown that information is sought out, evaluated, and used in a biased way in order to satisfy people's motivations to satisfy their psychological needs. This bias in information processing is broadly referred to as "motivated social cognition". Three general psychological needs people are motivated to satisfy include:

1. Managing threats: Motivations to eliminate perceived physical, emotional, or ideological threats
2. Reducing uncertainty: Motivations to reduce uncertainty, complexity, ambiguity, or disorder
3. Achieving social goals: Motivations for relationships with like-minded others and keeping groups distinct I propose that different forms of these motives may underlie vaccine outcomes and the processing of vaccine-related information.

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Randomization was done by the online survey platform (Qualtrics)

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Planned Missingness Design Block A

Respondents were randomized to complete one of three blocks (items predetermined by being randomized to blocks, with 1/3 of items in each block) of the psychological trait measures

Group Type EXPERIMENTAL