Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska

NCT ID: NCT07171255

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-22

Study Completion Date

2026-06-30

Brief Summary

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Alzheimer's disease and related dementias are a public health crisis impacting individuals across the world. In the United States, adults living in rural areas face an elevated risk for cognitive impairment mainly due to disparities in care, higher sedentary behavior, and reduced education. This project proposes to assess the impact of a remotely delivered exercise program (i.e., RemoteEx+) through a smartphone application. The app is programmed by our team and provides video demonstrations of exercises, workout regimes, motivational messaging, and weekly ADRD risk reduction education. The project aims to assess with a pre/post design the following aims:

* Aim 1. Assess the RemoteEx+ intervention exercise adherence, efficacy, enjoyment, and quality of life. We hypothesize that rural adults will report high exercise adherence (80% of session adherence), efficacy (\>50% on Self Efficacy for Exercise), and enjoyment (\>5.0 on Intrinsic Motivation Inventory - Interest / Enjoyment Subscale) and that these variables will be positively correlated with quality of life scores (36-Item Short Form Health Survey \[SF-36\])
* Aim 2. Determine the impact of a technology-driven exercise program on blood pressure and functional mobility associated with dementia risk. We hypothesize that the exercise program will result in improvements in blood pressure and functional mobility (2-minute step test and 30-second chair rise test) and that participants with high exercise adherence will see the greatest improvements in biomarkers associated with reduced dementia risk.
* Aim 3. Reduce health disparities among rural-dwelling Nebraska and Kansas residents. We hypothesize that RemoteEx+ will reduce barriers to exercise (Barriers to Being Active Quiz and improve knowledge surrounding dementia and modifiable risk factors (Dementia Knowledge Assessment Tool - Version 2 \[DKAT2\]) that will result in fewer lifestyle-related health disparities for the communities involved in this study.

The results from this project will inform whether RemoteEx+ has an impact on the stated outcomes above for adults living in rural areas.

Detailed Description

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Conditions

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Sedentary Middle Age and Older Aged Adults

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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RemoteEx+ Program

Group Type EXPERIMENTAL

RemoteEx+ Programming

Intervention Type BEHAVIORAL

The exercise program will include video instruction for all exercises, motivational cues, and ADRD risk education throughout the 16-week exercise program to encourage exercise adherence. RemoteEx+ is optimized to enhance exercise knowledge surrounding dementia risk factors to facilitate ADRD risk reduction and overall health improvement. The purpose of this study is to investigate the efficacy of RemoteEx+ on health outcomes associated with dementia risk in underactive rural adults.

Interventions

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RemoteEx+ Programming

The exercise program will include video instruction for all exercises, motivational cues, and ADRD risk education throughout the 16-week exercise program to encourage exercise adherence. RemoteEx+ is optimized to enhance exercise knowledge surrounding dementia risk factors to facilitate ADRD risk reduction and overall health improvement. The purpose of this study is to investigate the efficacy of RemoteEx+ on health outcomes associated with dementia risk in underactive rural adults.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age 40-85 years
* Characterized as underactive by the Telephone Assessment of Physical Activity (TAPA)50
* Self-reported proficiency in English
* Own a smartphone and willing to download an application
* Primary care provider clearance to participate for those who do not pass the PAR-Q+51
* Live in a rural area (Rural-Urban Commuting Area \[RUCA\] Codes) 52

Exclusion Criteria

* Contraindications to high-intensity exercise
* Cognitive impairment (\<19 on the Telephone Montreal Cognitive Assessment \[MoCA\])
* Neurodegenerative or acute neurological diagnoses (e.g., Parkinson's disease, stroke, traumatic brain injury)
* Orthopedic surgery or injuries in the last 6 months
Minimum Eligible Age

40 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Creighton University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Emporia State University

Emporia, Kansas, United States

Site Status RECRUITING

Creighton University

Omaha, Nebraska, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Rashelle Hoffman, PT, DPT, PhD

Role: CONTACT

402-546-8997

Erin Blocker, PhD

Role: CONTACT

Facility Contacts

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Role: primary

4022805691

Other Identifiers

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2005493

Identifier Type: -

Identifier Source: org_study_id

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