WBV Reflex Latency and Mechanical Load

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-02

Study Completion Date

2025-09-24

Brief Summary

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This study aims to investigate how the magnitude of mechanical loading affects reflex latency patterns induced by whole-body vibration (WBV). WBV can trigger two types of reflexes: the tonic vibration reflex (TVR) and the bone myoregulation reflex (BMR), which may be influenced by load-bearing condition. The study will include healthy adult volunteers aged 20-50 years. Reflex responses will be recorded from the soleus muscle using surface EMG during both WBV. Different conditions of mechanical loading (i.e., standing on one foot, both feet) and vibration frequencies (30-36 Hz) will be tested. The main outcome will be the latency of the reflex responses, which will help distinguish between TVR and BMR activation. The goal is to better understand how mechanical load modifies reflex response timing and to characterize the underlying afferent pathways. This knowledge may contribute to optimizing vibration-based rehabilitation strategies.

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Detailed Description

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This study investigates how the magnitude of mechanical loading alters reflex latency patterns during whole-body vibration (WBV), focusing specifically on the tonic vibration reflex (TVR) and the bone myoregulation reflex (BMR). Experimental data suggest that WBV may activate different reflex mechanisms depending on the level of postural loading, frequency, and amplitude of the vibration. Previous studies have shown that low-amplitude WBV tends to activate TVR under voluntary contraction, while higher mechanical loads and neutral standing posture are more likely to induce BMR.

Surface electromyography (sEMG) recordings will be obtained from the soleus muscle during vibration stimuli applied at different frequencies (30, 32, 34, and 36 Hz). Recordings will be taken under multiple loading conditions: standing on both feet, standing on one foot. Reflex latency will be calculated using cumulative averaging techniques, and data will be analyzed offline using Spike2 software.

Findings from this study may contribute to a deeper understanding of reflex integration during vibratory stimulation and inform future neurorehabilitation protocols that utilize WBV as a therapeutic modality.

Conditions

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Whole-body Vibration Healthy Volunteers (HV) Muscle Contraction Postural Balance Electromyography

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

All participants receive the same sequence of whole-body vibration under different loading conditions. There is no randomization or control group. This is a single-arm, within-subject experimental design evaluating reflex latency under multiple biomechanical scenarios.

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Whole-Body Vibration in Healthy Volunteers

Participants will receive whole-body vibration (WBV) under mechanical loading conditions. Surface EMG recordings from the soleus muscle will be used to evaluate reflex latency at vibration frequencies of 30, 32, 34, and 36 Hz. All interventions will be applied in a single-session experimental design in healthy adult volunteers.

Group Type EXPERIMENTAL

Whole-Body Vibration

Intervention Type DEVICE

Participants will receive whole-body vibration (WBV) at 30-36 Hz under different mechanical loading conditions (e.g., standing on one foot, both feet,). Vibration-induced reflex responses will be recorded from the soleus muscle using surface electromyography. The intervention is designed to evaluate latency differences between tonic vibration reflex (TVR) and bone myoregulation reflex (BMR) under controlled biomechanical scenarios.

Interventions

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Whole-Body Vibration

Participants will receive whole-body vibration (WBV) at 30-36 Hz under different mechanical loading conditions (e.g., standing on one foot, both feet,). Vibration-induced reflex responses will be recorded from the soleus muscle using surface electromyography. The intervention is designed to evaluate latency differences between tonic vibration reflex (TVR) and bone myoregulation reflex (BMR) under controlled biomechanical scenarios.

Intervention Type DEVICE

Other Intervention Names

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WBV Reflex Latency Vibration Protocol

Eligibility Criteria

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Inclusion Criteria

* Aged between 18 and 40 years
* Healthy adult volunteers with no known neurological or musculoskeletal disorders
* Able to provide informed consent
* Willing to comply with the procedures of the study, including EMG and vibration exposure

Exclusion Criteria

* History of any neurological condition (e.g., peripheral neuropathy, spinal cord injury, stroke)
* Musculoskeletal injury or surgery involving the lower extremities
* Use of medications affecting neuromuscular function
* Pregnancy
* Presence of implanted electronic devices (e.g., pacemaker)
* Known intolerance to vibration exposure

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes