Treatment Effectiveness in People With axSpA or PsA Starting Treatment With Bimekizumab, Risankizumab, Guselkumab, Upadacitinib, or a TNF Inhibitor

NCT ID: NCT07166315

Last Updated: 2025-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-07

Study Completion Date

2027-03-31

Brief Summary

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This observational study will target patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) who have started treatment with bimekizumab, upadacitinib, risankizumab, guselkumab, or a tumour necrosis factor-alpha inhibitor (e.g., adalimumab or etanercept) at NHS hospitals in the United Kingdom. Information from patients' medical records will be collected, and patients will complete surveys about their experiences with their treatment. The study will look at treatment effectiveness from both healthcare professionals' and patients' points of view.

Detailed Description

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Patient experience surveys will be administered prospectively throughout the study period, whereas the review of patients' medical records will be conducted retrospectively towards the end of the study period.

Conditions

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Axial Spondylarthritis (axSpA) Psoriatic Arthritis (PsA)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Axial spondyloarthritis (axSpA)

Patients diagnosed with axial spondyloarthritis (axSpA) who are initiating treatment with bimekizumab, upadacitinib, or a tumour necrosis factor-alpha inhibitor.

observational study

Intervention Type OTHER

This is an observational study based on existing treatments prescribed prior to inclusion. No interventions are given as part of this research.

Psoriatic arthritis (PsA)

Patients diagnosed with psoriatic arthritis (PsA) who are initiating treatment with bimekizumab, upadacitinib, risankizumab, guselkumab or a tumour necrosis factor-alpha inhibitor.

observational study

Intervention Type OTHER

This is an observational study based on existing treatments prescribed prior to inclusion. No interventions are given as part of this research.

Interventions

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observational study

This is an observational study based on existing treatments prescribed prior to inclusion. No interventions are given as part of this research.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Participant has a clinical diagnosis of axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA).
* Participant has been prescribed advanced therapy within one month prior to enrolment in the study, to treat their axSpA or PsA.
* Participant is aged 18 years or older at enrolment.

Exclusion Criteria

-Participation in a clinical trial at enrolment.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Adelphi Real World

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Royal National Hospital for Rheumatic Diseases

Bath, Somerset, United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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SpA Extend Team

Role: CONTACT

+441625 577 829

Facility Contacts

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Clare Davey

Role: primary

01225821800

Other Identifiers

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AG9827

Identifier Type: -

Identifier Source: org_study_id

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