Surface EMG Testing on Swallowing in EoE Patients

NCT ID: NCT07156357

Last Updated: 2025-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-04

Study Completion Date

2027-06-30

Brief Summary

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Evaluating swallowing food with surface electromyography (EMG) machine in patients with Eosinophilic Esophagitis

Detailed Description

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Evaluating surface electromyography (sEMG) assessment of swallowing and bolus preparation in patients with Eosinophilic Esophagitis (EoE).

Conditions

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Eosinophilic Esophagitis (EoE)

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Controls

Subjects who can swallow normally

Surface Electromyography

Intervention Type DIAGNOSTIC_TEST

Tests performed to evaluate swallowing function

Fiberoptic Endoscopic Evaluation of Swallowing

Intervention Type DIAGNOSTIC_TEST

Assessment of swallowing function

Eosinophilic Esophagitis

Subjects with Eosinophilic Esophagitis

Surface Electromyography

Intervention Type DIAGNOSTIC_TEST

Tests performed to evaluate swallowing function

Fiberoptic Endoscopic Evaluation of Swallowing

Intervention Type DIAGNOSTIC_TEST

Assessment of swallowing function

Interventions

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Surface Electromyography

Tests performed to evaluate swallowing function

Intervention Type DIAGNOSTIC_TEST

Fiberoptic Endoscopic Evaluation of Swallowing

Assessment of swallowing function

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Controls

* Normal video swallow or score of 0 for dysphagia on ESSAI questionnaire
* absence of dysphagia
* age \>18 EoE participants
* Documentation of EoE diagnosis by histologic criteria,
* \>15 eos/hpf on most recent esophageal biopsy
* age \>18

Exclusion Criteria

* Abnormal baseline video swallow
* lack of MSK coordination to eat test meal
* underlying neuromuscular disorder.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Karthik Ravi, M.D.

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karthik Ravi, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Ryan Alexander, MD

Role: CONTACT

507-284-4824

Mariah Robran, CCRP

Role: CONTACT

507-266-3595

Facility Contacts

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Mariah Robran, CCRP

Role: primary

507-266-3595

Other Identifiers

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24-009832

Identifier Type: -

Identifier Source: org_study_id

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