Hepatitis B Virus Reactivation in COVID-19

NCT ID: NCT07154212

Last Updated: 2025-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1793 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-01

Study Completion Date

2022-04-08

Brief Summary

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The aim of this observational cohort study was to evaluate adherence to hepatitis B virus (HBV) screening guidelines in a country characterized by low HBV prevalence and assess the potential reactivation and progression of HBV infection in anti-HBV core antigen antibodies (anti-HBc) positive patients receiving corticosteroids for coronavirus disease 2019 (COVID-19).

Detailed Description

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Conditions

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COVID-19 Pneumonia Hypoxemia Hepatitis B

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Hepatitis B virus infected patients receiving corticosteroids for COVID-19 pneumonia

Hepatitis B virus infection

Intervention Type DIAGNOSTIC_TEST

anti-hepatitis B virus core antigen positive serologic status

Interventions

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Hepatitis B virus infection

anti-hepatitis B virus core antigen positive serologic status

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* hospitalized adult patients with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) polymerase chain reaction (PCR) test
* supplemental oxygen
* treated with corticosteroids for COVID-19 pneumonia

Exclusion Criteria

* age under 18 years
* hospitalized for medical conditions unrelated to COVID-19
* received corticosteroid therapy for non-COVID-19 reasons
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Medical Centre Ljubljana

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Medical Centre Ljubljana

Ljubljana, , Slovenia

Site Status

Countries

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Slovenia

Other Identifiers

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HBV in covid

Identifier Type: -

Identifier Source: org_study_id

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