Sustainability and Precision Prevention Project

NCT ID: NCT07153042

Last Updated: 2025-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

3705 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-01

Study Completion Date

2029-11-30

Brief Summary

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This is a five-year hybrid type 3 effectiveness-implementation study evaluating multilevel strategies to sustain a nationwide implementation of an evidence-based HIV prevention curriculum in schools. Advanced machine learning methods are being used to enhance implementation strategies. A Sequential, Multiple Assignment, Randomized Trial (SMART) design will be employed.

Detailed Description

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A hybrid type 3 effectiveness-implementation study is proposed, using a SMART adaptive implementation trial that will evaluate the value of multilevel strategies to sustain Focus on Youth in Caribbean + Caribbean Informed Parents and Children Together (FOYC+CImPACT) in schools and harness advanced machine learning to help promote the FOYC+CImPACT sustainability by iteratively enriching implementation strategies. This study will also identify the most effective implementation strategy for teachers who implement \<80% of core activities and for adolescents who are unlikely to respond to FOYC+CImPACT by using machine learning approaches. The primary outcome is program sustainability. Data from teachers, students, and focus groups will provide information on inner and outer contexts, strategies to promote implementation and sustainability, and program effectiveness.

Primary implementation of FOYC+CImPACT will be conducted by 156 grade-6 teachers in 65 government primary schools across four years. Annual FOYC booster sessions for students will be conducted by 49 Health and Family Life Education (HFLE) teachers in 30 junior high schools. Approximately 3,500 students will complete the full curricular assessment survey at the beginning and end of grade 6 and at the end of grades 7, 8, and 9.

Conditions

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Sustainability

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Stage 1

All grade six teachers will go through the Usual Implementation (UI) of FOYC+CImPACT (teacher training only in Year 1).

Group Type EXPERIMENTAL

FOYC+CImPACT

Intervention Type BEHAVIORAL

Focus on Youth in the Caribbean (FOYC) is an evidence-based, eight-session life skills curriculum designed to reduce risk-taking behaviors related to HIV/STI transmission and teen pregnancy. Woven throughout FOYC is a decision-making model that provides guidance and practice in problem solving with a focus on how to obtain factual information on sexual health.

CImPACT is a single-session intervention including a 24-min educational video filmed in The Bahamas. The video focuses on effective parent-adolescent communication and listening strategies related to difficult topics including "safe-sex" followed by two role-plays for the parent and youth, a discussion, and a condom demonstration.

Stage 2

Based on their performance in Year 1, teachers who do not meet the benchmark (implementing \> 80% of core activities) will be randomized to receive 1) "Biweekly Monitoring and Feedback (BMF)" or 2) "BMF+Site-Based Assistance Mentorship (SAM)." Responders (completing at least 80% of core activities) will continue with UI.

Group Type EXPERIMENTAL

Biweekly monitoring and feedback (BMF)

Intervention Type BEHAVIORAL

School coordinators will monitor teachers' implementation progress biweekly and provide feedback to teachers.

Site-based assistance and mentorship (SAM)

Intervention Type BEHAVIORAL

High-performing teachers will serve as team leaders and guide non-responding teachers on preparation and planning. The team leader will promote group activities and enhance interaction among teachers in these meetings.

FOYC+CImPACT

Intervention Type BEHAVIORAL

Focus on Youth in the Caribbean (FOYC) is an evidence-based, eight-session life skills curriculum designed to reduce risk-taking behaviors related to HIV/STI transmission and teen pregnancy. Woven throughout FOYC is a decision-making model that provides guidance and practice in problem solving with a focus on how to obtain factual information on sexual health.

CImPACT is a single-session intervention including a 24-min educational video filmed in The Bahamas. The video focuses on effective parent-adolescent communication and listening strategies related to difficult topics including "safe-sex" followed by two role-plays for the parent and youth, a discussion, and a condom demonstration.

Stage 3

At the end of Year 2 (stage 2), the performance of the teachers in all three intervention arms will be assessed again. Non-responders in the UI arm will be re-randomized to receive either BMF or BMF+SAM. Non-responders in the BMF-only group will be re-randomized to receive BMF+SAM or BMF+enhanced SAM. Non-responders in the BMF+SAM group will receive BMF+enhanced SAM.

Group Type EXPERIMENTAL

Biweekly monitoring and feedback (BMF)

Intervention Type BEHAVIORAL

School coordinators will monitor teachers' implementation progress biweekly and provide feedback to teachers.

Site-based assistance and mentorship (SAM)

Intervention Type BEHAVIORAL

High-performing teachers will serve as team leaders and guide non-responding teachers on preparation and planning. The team leader will promote group activities and enhance interaction among teachers in these meetings.

Enhanced site-based assistance and mentorship (Enhanced SAM)

Intervention Type BEHAVIORAL

A FOYC coach (with FOYC implementation and training experience) will provide tailored in-person support, facilitate goal-setting, opportunities to interact with consultants, supportive text messaging, continuing education, networking strategies, and monthly check-ins.

FOYC+CImPACT

Intervention Type BEHAVIORAL

Focus on Youth in the Caribbean (FOYC) is an evidence-based, eight-session life skills curriculum designed to reduce risk-taking behaviors related to HIV/STI transmission and teen pregnancy. Woven throughout FOYC is a decision-making model that provides guidance and practice in problem solving with a focus on how to obtain factual information on sexual health.

CImPACT is a single-session intervention including a 24-min educational video filmed in The Bahamas. The video focuses on effective parent-adolescent communication and listening strategies related to difficult topics including "safe-sex" followed by two role-plays for the parent and youth, a discussion, and a condom demonstration.

Interventions

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Biweekly monitoring and feedback (BMF)

School coordinators will monitor teachers' implementation progress biweekly and provide feedback to teachers.

Intervention Type BEHAVIORAL

Site-based assistance and mentorship (SAM)

High-performing teachers will serve as team leaders and guide non-responding teachers on preparation and planning. The team leader will promote group activities and enhance interaction among teachers in these meetings.

Intervention Type BEHAVIORAL

Enhanced site-based assistance and mentorship (Enhanced SAM)

A FOYC coach (with FOYC implementation and training experience) will provide tailored in-person support, facilitate goal-setting, opportunities to interact with consultants, supportive text messaging, continuing education, networking strategies, and monthly check-ins.

Intervention Type BEHAVIORAL

FOYC+CImPACT

Focus on Youth in the Caribbean (FOYC) is an evidence-based, eight-session life skills curriculum designed to reduce risk-taking behaviors related to HIV/STI transmission and teen pregnancy. Woven throughout FOYC is a decision-making model that provides guidance and practice in problem solving with a focus on how to obtain factual information on sexual health.

CImPACT is a single-session intervention including a 24-min educational video filmed in The Bahamas. The video focuses on effective parent-adolescent communication and listening strategies related to difficult topics including "safe-sex" followed by two role-plays for the parent and youth, a discussion, and a condom demonstration.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Grade 6 teachers who teach Health and Family Life Education (HFLE) and their classes in 65 government primary schools.
* Grade 7-9 HFLE teachers and their classes in 30 middle schools across 12 Bahamian islands.
* FOYC (Focus on Youth in the Caribbean) is delivered as part of the standard HFLE curriculum.
* Students who: 1) are enrolled in one of the participating schools as general education students in grade 6 (and followed through grades 7-9); and 2) speak and read English.

Exclusion Criteria

* Students who chose to opt out of participating in the study
* Students who do not speak or read English sufficiently to participate in study activities.
Minimum Eligible Age

10 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

Sponsor Role collaborator

Ministry of Health, Bahamas

UNKNOWN

Sponsor Role collaborator

University of Massachusetts, Worcester

OTHER

Sponsor Role lead

Responsible Party

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Bo Wang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bo Wang, PhD

Role: PRINCIPAL_INVESTIGATOR

UMass Chan Medical School

Locations

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HIV/AIDS Office, FOY program

Nassau, , The Bahamas

Site Status RECRUITING

Countries

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The Bahamas

Central Contacts

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Lynette Deveaux

Role: CONTACT

1-242-454-8488

Deogwoon Kim, PhD

Role: CONTACT

Facility Contacts

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Lynette Deveaux

Role: primary

1-242-454-8488

Other Identifiers

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STUDY00002463

Identifier Type: -

Identifier Source: org_study_id

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