Cardiological Drug Classes And Falls in Older Adults

NCT ID: NCT07150754

Last Updated: 2025-09-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-02

Study Completion Date

2025-07-01

Brief Summary

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Heat failure is a fast gowing health issue with a rising incidence in older adults. Recommendations have recently been published to treat heart failure, but most clinical trials leading to these recommendations tended to exclude older adults.

Older adults are at higher risk of falls and severe consequences of falls. All heart failure treatments are at risk of causing a fall through different mechanisms.

Based on the World Health Organization global database, the main objective of this study is to investigate the association between heart failure pharmacological treatments and the report of a fall in the database.

A disproportionality analysis will be performed. It will aim to assess whether some classes of heart failure drugs, and within these classes some individual drugs, are associated with a report of a fall.

A sensibilty analysis will also be performed. It will aim to examine the association between takien a heart failure pharmacological treatment, with a heat failure indication and/or a loop diuretic, and the report of a fall.

Detailed Description

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Conditions

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Heart Failure Fall

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Heart failure pharmacological treatments

Identify a positive signal for fall with one or more of the recommended pharmacological treatments for heart failure

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age 65 years of older

Exclusion Criteria

\-
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Caen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Caen University Hospital, Department of Pharmacology

Caen, Normandy, France

Site Status

Countries

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France

Other Identifiers

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PHARMACOGERIA092025

Identifier Type: -

Identifier Source: org_study_id

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