Green Tea Extract and Ginger

NCT ID: NCT07150533

Last Updated: 2025-09-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-01

Study Completion Date

2025-07-30

Brief Summary

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This study investigates the effects of green tea extract and ginger supplementation, both individually and in combination, on endurance performance, metabolism, thermal comfort, and muscle soreness in recreationally active young men. Participants will complete cycling tests under both normal room temperature (21-24°C) and cold (5-7°C) conditions. The study uses a randomized, double-blind, placebo-controlled, crossover design to compare the outcomes of placebo, green tea, ginger, and combined supplementation. The findings may help to identify nutritional strategies that improve exercise performance and comfort in different environmental conditions.

Detailed Description

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This randomized, double-blind, placebo-controlled, crossover trial is designed to evaluate the effects of green tea extract and ginger supplementation, both individually and in combination, on endurance performance, metabolic responses, thermal sensation, and muscle soreness in recreationally active men.

Sixteen healthy participants will complete eight experimental conditions: placebo, green tea extract (500 mg), ginger (1 g), and a combination of both, tested under normal (21-24°C) and cold (5-7°C) environments. Each condition will be separated by a washout period to avoid carryover effects.

Endurance capacity will be measured using a time-to-exhaustion cycling test at 70% of maximal oxygen uptake (VO₂max). Metabolic responses will be assessed by gas analysis to determine respiratory exchange ratio (RER). Perceptual measures will include the Borg Rating of Perceived Exertion (RPE) and a thermal sensation scale, while muscle soreness will be evaluated 24 hours post-exercise using a visual analog scale (VAS).

The study aims to determine whether the combined intake of green tea and ginger provides synergistic benefits over individual supplementation, particularly in cold environments where thermoregulation and endurance capacity are challenged. Findings may contribute to practical nutritional strategies that enhance exercise performance, comfort, and recovery under environmental stress conditions.

Conditions

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Nutritional Supplementation Exercise Physiology

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Placebo Arm

Participants receive a placebo consisting of maltodextrin in capsule form, matched in appearance and taste to the active supplements.

Group Type PLACEBO_COMPARATOR

Placebo Arm

Intervention Type DIETARY_SUPPLEMENT

Participants receive a placebo consisting of maltodextrin in capsule form, matched in appearance and taste to the active supplements.

Green Tea Extract Arm

Participants receive 500 mg of standardized green tea extract in capsule form.

Group Type EXPERIMENTAL

Green Tea Extract

Intervention Type DIETARY_SUPPLEMENT

Participants receive 500 mg of standardized green tea extract in capsule form.

Ginger Arm

Participants receive 1 g of ginger supplement in capsule form.

Group Type EXPERIMENTAL

Ginger

Intervention Type DIETARY_SUPPLEMENT

Participants receive 1 g of ginger supplement in capsule form.

Combined Supplement Arm

Participants receive a combination of 500 mg green tea extract and 1 g ginger, both administered in capsule form.

Group Type EXPERIMENTAL

Combined Supplement (Green Tea + Ginger)

Intervention Type DIETARY_SUPPLEMENT

Participants receive a combination of 500 mg green tea extract and 1 g ginger, both administered in capsule form.

Interventions

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Placebo Arm

Participants receive a placebo consisting of maltodextrin in capsule form, matched in appearance and taste to the active supplements.

Intervention Type DIETARY_SUPPLEMENT

Green Tea Extract

Participants receive 500 mg of standardized green tea extract in capsule form.

Intervention Type DIETARY_SUPPLEMENT

Ginger

Participants receive 1 g of ginger supplement in capsule form.

Intervention Type DIETARY_SUPPLEMENT

Combined Supplement (Green Tea + Ginger)

Participants receive a combination of 500 mg green tea extract and 1 g ginger, both administered in capsule form.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

Male participants aged 18-35 years

Recreationally active (≥3 aerobic exercise sessions per week, ≥30 minutes per session, for at least 6 months)

VO₂max between 40-50 mL/kg/min (recreationally active fitness level)

Body mass index within the normal to slightly overweight range (approximately 18.5-27.5 kg/m²)

Willingness to comply with study requirements, including supplementation and exercise testing protocols

Provided written informed consent

Exclusion Criteria

History of cardiovascular, respiratory, metabolic, or neurological disorders

Allergy or intolerance to green tea, ginger, or maltodextrin

Current use of ergogenic supplements, medications affecting metabolism, or stimulants (e.g., beta-blockers, caffeine pills)

Smoking or excessive alcohol consumption (\>14 units per week)

Inconsistent exercise habits (\<3 sessions/week in the past 6 months)

Participation in another clinical trial within the past 3 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Erzurum Technical University

OTHER

Sponsor Role lead

Responsible Party

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Süleyman Ulupınar

Associate Professor of Exercise Physiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Erzurum Technical University Sport Sciences Faculty

Erzurum, Erzurum, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Demirli A, Ulupinar S, Terzi M, Ozbay S, Ozkara AB, Gencoglu C, Ouergui I, Ardigo LP. Synergistic Effects of Green Tea Extract and Ginger Supplementation on Endurance Performance and Thermal Perception in Normothermic and Cold Environments: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial. Nutrients. 2025 Sep 13;17(18):2949. doi: 10.3390/nu17182949.

Reference Type DERIVED
PMID: 41010475 (View on PubMed)

Other Identifiers

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ETU-Green Tea and Ginger

Identifier Type: -

Identifier Source: org_study_id

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