Correlation Between Stages of Mandibular 2nd Molar Calcification and CVMI for Assessment of Skeletal Maturation: A Cross Sectional Study

NCT ID: NCT07141602

Last Updated: 2025-08-26

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Total Enrollment: 212 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-09-01
• Study Completion Date: 2026-07-01

Brief Summary

The aims of this study will be:

1. To investigate the relationships between mandibular second molar calcification stages and skeletal maturity in Egyptian population, and

2. To evaluate whether the mandibular second molar calcification stages can be used as a reliable diagnostic tool to assess skeletal maturity in Egyptian population.

Detailed Description

This cross-sectional study will include 106 Egyptian subjects with age range between 9 and 18 years old, who will present to outpatient clinic of Orthodontic department, Faculty of Dentistry, Cairo University, and will be classified according to their gender into two groups (males and females). Radiographs (panorama and cephalogram) will be collected from all study participants who meet inclusion criteria for data analysis. The inclusion criteria will be as follows:

• Chronological age ranging from 9 to 18 years
• No serious illness
• Normal overall growth and development
• Absence of abnormal dental conditions, such as impaction, transposition, and congenitally missing teeth
• Absence of previous history of trauma or disease to the face and neck
• Absence of orthodontic treatment
• No permanent teeth extracted

We will obtain panoramic and lateral cephalometric radiographs of 106 Egyptian subjects from the pretreatment records of patients attending clinics for orthodontic treatment.

All radiographic assessments will be performed in a darkened room. Any radiograph that shows motion dullness or has poor contrast will be discarded. A single radiologist will expose and develop all radiographs.

Conditions

Correlation Between Second Molar Calcification Stage and CVMI for Skeletal Maturation Assessment in Egyptian Population

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

will include males

lateral cephalometric x- ray and dental panoramic tomogram

Intervention Type: DIAGNOSTIC_TEST

lateral cephalometric x- ray and dental panoramic tomogram

will include females

lateral cephalometric x- ray and dental panoramic tomogram

Intervention Type: DIAGNOSTIC_TEST

lateral cephalometric x- ray and dental panoramic tomogram

Interventions

lateral cephalometric x- ray and dental panoramic tomogram

lateral cephalometric x- ray and dental panoramic tomogram

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• • Chronological age ranging from 9 to 18 years

• No serious illness
• Normal overall growth and development
• Absence of abnormal dental conditions, such as impaction, transposition, and congenitally missing teeth
• Absence of previous history of trauma or disease to the face and neck
• Absence of orthodontic treatment
• No permanent teeth extracted

Exclusion Criteria

-

• Minimum Eligible Age: 9 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Mohamed Abd El-Ghafour

OTHER

Sponsor Role: lead

Responsible Party

Mohamed Abd El-Ghafour

Mohamed Abd El-Ghafour Omar, BDS, MSc, PhD

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

Faculty of Dentistry-Cairo University

Gizah-Egypt, , Egypt

Countries

Egypt

Other Identifiers

ORTH7-3-2

Identifier Type: -

Identifier Source: org_study_id