Comparison of Distal IPACK and Popliteal Plexus Block Combined With Femoral Triangle Block After Total Knee Arthroplasty
NCT ID: NCT07130552
Last Updated: 2025-09-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
120 participants
INTERVENTIONAL
2025-08-29
2026-04-30
Brief Summary
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Detailed Description
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The IPACK (interspace between the popliteal artery and capsule of the posterior knee) block is a regional anesthesia technique in which a local anesthetic is infiltrated under ultrasound guidance between the popliteal artery and the capsule of the posterior knee. This technique blocks the branches of the obturator nerve, the common peroneal nerve, and the tibial nerve in the popliteal region. In the context of knee arthroplasty, the application of the IPACK block has been associated with lower scores for ambulatory pain, lower scores for resting pain, and reduced morphine consumption.
Although both techniques of blockade seem to be efficient in the context of analgesia for the posterior part of the knee after TKA. No study compares these two blocks as part of multimodal analgesia to provide pain relief after TKA.
This study aimed to evaluate the analgesic effect of PPB or distal IPACK, in addition to femoral triangle block, as a component of a multimodal analgesic regimen after TKA.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Group Popliteal plexus block
femoral triangle block and popliteal plexus block
femoral triangle block and popliteal plexus block
Single dose bolus, 10 ml 5% bupivacaine will be used for FTB, 10 ml 5% bupivacaine will be used for PPB
Group distal iPACK
Femoral triangle block and distal iPACK
Femoral triangle block and distal iPACK
Single dose bolus, 10 ml 5% bupivacaine will be used for FTB, 10 ml 5% bupivacaine will be used for distal iPACK
Interventions
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femoral triangle block and popliteal plexus block
Single dose bolus, 10 ml 5% bupivacaine will be used for FTB, 10 ml 5% bupivacaine will be used for PPB
Femoral triangle block and distal iPACK
Single dose bolus, 10 ml 5% bupivacaine will be used for FTB, 10 ml 5% bupivacaine will be used for distal iPACK
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists (ASA) status I-III
* Patients who give informed consent
Exclusion Criteria
* Kidney disease with GFR \< 50 ml/min
* Daily opioid consumption \> 1 month
* Allergy to local anesthetics
* Neurological problems of the lower extremity
* Contraindications to peripheral nerve blocks
18 Years
85 Years
ALL
No
Sponsors
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Karaman Training and Research Hospital
OTHER
Responsible Party
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Locations
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Karaman Training and Research Hospital, Karaman, Karaman 70200
Karaman, Karaman, Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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06-2022/16
Identifier Type: -
Identifier Source: org_study_id
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