Outcomes and Prognostic Factors of Acute Mastoiditis in the Grand-Est Region
NCT ID: NCT07122440
Last Updated: 2025-08-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
326 participants
OBSERVATIONAL
2024-03-02
2025-07-31
Brief Summary
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Data of children with acute mastoiditis of the last ten years in five hospitals of the North-East of France (University Hospitals of Nancy, Strasbourg, Dijon, Besançon and the Regional Hospital of Metz-Thionville) will be analyzed.
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Detailed Description
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These complications can be divided into two categories according to their topography:
* intracranial complications : thrombophlebitis, meningitis, epidural abscess, and cerebral empyema.
* Extracranial complications subperiosteal abscess, Bezold's abscess, peripheral facial paralysis, labyrinthitis, and temporomandibular joint arthritis.
Incidence ranges from 1.2 to 6 per 100,000 children per year, with a trend of increasing cases with the increase in the proportion of Fusobacterium Necrophorum infections, described as frequent provider of complications. This observation is shared by the ENT practitioners of the CHRU of Nancy.
The management of mastoiditis is medico-surgical, but the therapeutic algorithms vary according to the centers and countries. The exact place of surgery is discussed in uncomplicated cases, despite recent meta-analyses. In France, no therapeutic algorithm is currently proposed by ENT societies.
Given this double observation of increased incidence and lack of homogeneity in the management of mastoiditis, it appears to be useful to refine the epidemiological knowledge on this pathology.
Therefore, we will analyze data of children with acute mastoiditis of the last ten years in five hospitals of the North-East of France : University Hospitals of Nancy, Strasbourg, Dijon, Besançon and the Regional Hospital of Metz-Thionville.
Conditions
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Study Design
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OTHER
RETROSPECTIVE
Interventions
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acute mastoiditis
retrospective data collection from clinical charts
Eligibility Criteria
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Inclusion Criteria
* Supported in one of the ENT or pediatric services of the four investigation centers
* Between January 1, 2014 and July 31, 2024
* With a diagnosis of acute mastoiditis
Exclusion Criteria
15 Years
ALL
No
Sponsors
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Cécile RUMEAU
OTHER
Responsible Party
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Cécile RUMEAU
Head of Otolaryngology
Locations
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University Hospital Center of Nancy
Vandœuvre-lès-Nancy, , France
Countries
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Other Identifiers
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2023PI213
Identifier Type: -
Identifier Source: org_study_id
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