The Effect of Multimodal Treatment of Rectal Cancer on Circulating Tumor Cells: A Prospective, Observational Study

NCT ID: NCT07112937

Last Updated: 2025-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-02

Study Completion Date

2027-12-31

Brief Summary

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The prospective study will focus on patients undergoing multimodal treatment for rectal cancer. The main objective of the study will be to monitor changes in circulating tumor cells (CTCs) in the peripheral blood of patients during multimodal treatment. For each patient enrolled in the study, peripheral blood samples will be collected at specified time intervals to determine the presence and quantity of CTCs.

The CTCs levels will be compared among rectal cancer patients with neoadjuvant chemoradiotherapy and without neoadjuvant chemotherapy.

Detailed Description

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Conditions

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Rectal Cancer Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Rectal cancer patients with neoadjuvant chemoradiotherapy

No interventions assigned to this group

Rectal cancer patients without neoadjuvant chemoradiotherapy

No interventions assigned to this group

Eligibility Criteria

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Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Institute of Molecular and Translational Medicine, Czech Republic

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Hospital Ostrava

Ostrava, , Czechia

Site Status RECRUITING

Countries

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Czechia

Central Contacts

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Josef Srovnal, Associate professor, MD, PhD

Role: CONTACT

+420 585632137

Facility Contacts

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Peter Ihnat, Profesor, MD, PhD.

Role: primary

420 597 375 701

References

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Ihnat P, Srovnal J, Hrubovcak J, Martinek L. Detection and clinical significance of circulating tumour cells in patients with colorectal carcinoma. Rozhl Chir. 2023;102(10):376-380. doi: 10.33699/PIS.2023.102.10.376-380.

Reference Type BACKGROUND
PMID: 38302423 (View on PubMed)

Other Identifiers

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LF_2023_0118

Identifier Type: OTHER

Identifier Source: secondary_id

01/RVO-FNOs/2023

Identifier Type: -

Identifier Source: org_study_id

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