A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease
NCT ID: NCT07106021
Last Updated: 2026-01-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE1/PHASE2
12 participants
INTERVENTIONAL
2025-07-17
2031-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SEQUENTIAL
TREATMENT
NONE
Study Groups
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First patient group
Low dose
RNDP-001
Stem cells
Syringe Front-Loading Device
Delivers the stem cells
Second patient group
High dose
RNDP-001
Stem cells
Syringe Front-Loading Device
Delivers the stem cells
Third patient group
Best dose
RNDP-001
Stem cells
Syringe Front-Loading Device
Delivers the stem cells
Interventions
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RNDP-001
Stem cells
Syringe Front-Loading Device
Delivers the stem cells
Eligibility Criteria
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Inclusion Criteria
* Age 45 to 75
* Medically stable to undergo a surgical procedure
Exclusion Criteria
* Previous infusion therapy or surgery for Parkinson's disease
* History of allergic reaction or intolerance to an immunotherapeutic agent
* Contraindication to MRI
* Clinically significant medical conditions likely to interfere with the surgical procedure or study assessments
45 Years
75 Years
ALL
No
Sponsors
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California Institute for Regenerative Medicine (CIRM)
OTHER
Kenai Therapeutics
INDUSTRY
Responsible Party
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Locations
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University of Arizona
Tucson, Arizona, United States
Keck Medical Center of University of Southern California
Los Angeles, California, United States
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States
Countries
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Central Contacts
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Facility Contacts
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Role: primary
Related Links
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Related Info
Other Identifiers
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RNDP-001-02
Identifier Type: -
Identifier Source: org_study_id
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