Carotid Endarterectomy Versus Stenting in Patients With Acute Stage of Ischemic Stroke.
NCT ID: NCT07083986
Last Updated: 2025-07-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
50 participants
INTERVENTIONAL
2025-05-21
2028-05-21
Brief Summary
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Patient inclusion criteria:
1. Ischemic stroke in the middle cerebral artery territory
2. Ipsilateral stenosis of the internal carotid artery more than 50%
3. Neurological deficit at the time of surgical treatment: the modified Rankin scale (mRs) score of 0-4 and the US National Institutes of Health (NIHSS) stroke scale score no more than 12
4. The size of the ischemia focus: no more than 1/3 in the territory of the middle cerebral artery brain supply
5. Terms of operation: from 1 to 28 days from the moment of ischemic stroke
The primary intra-hospital and/or 30-day study endpoints:
1. Perioperative ipsilateral ischemic stroke.
2. Any stroke: contralateral ischemic or any hemorrhagic stroke.
3. Myocardial infarction.
4. Hemorrhagic complications that required surgical revision of the operating wound or transfusion of blood components.
5. Surgical site infection
6. Death
7. Main adverse cardiovascular events (stroke + myocardial infarction + death).
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SEQUENTIAL
TREATMENT
NONE
Study Groups
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Patients in acute period of Ischaemic Stroke
Carotid Artery Stent Placement
Carotid Artery Stent Placement was performed according to the standard technique.
carotid endarterectomy
Carotid endarterectomy with stenting was performed according to the standard technique. For the purpose of the greatest comparability in the volume of anesthesia, it was decided to use regional anesthesia in all cases, including adequate dynamic observation of neurological status.
Interventions
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Carotid Artery Stent Placement
Carotid Artery Stent Placement was performed according to the standard technique.
carotid endarterectomy
Carotid endarterectomy with stenting was performed according to the standard technique. For the purpose of the greatest comparability in the volume of anesthesia, it was decided to use regional anesthesia in all cases, including adequate dynamic observation of neurological status.
Eligibility Criteria
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Inclusion Criteria
18 Years
ALL
No
Sponsors
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Pirogov Russian National Research Medical University
OTHER
Responsible Party
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Pryamikov Aleksandr
MD, PhD (DMedSc [Russia]), Associate Professor
Locations
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Moscow City Clinical Hospital named after V.M. Buyanov
Moscow, , Russia
Countries
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Other Identifiers
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25225062025
Identifier Type: -
Identifier Source: org_study_id
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