CT and Endoscopic Biopsy Image-Based Deep Learning for Predicting Left Recurrent Laryngeal Nerve Lymph Node Metastasis in Esophageal Cancer

NCT ID: NCT07074535

Last Updated: 2025-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2027-12-30

Brief Summary

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The goal of this observational study is to develop a predictive model for left recurrent laryngeal nerve (RLN) lymph node metastasis using deep learning algorithms. The model will be developed using clinical data from previous esophageal cancer surgeries, including preoperative CT imaging, and histopathological images from gastroscopic biopsies. The model will also be validated through prospective clinical trials to guide the intraoperative lymph node dissection, thereby reducing postoperative risks of RLN injury.

Detailed Description

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Conditions

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Esophageal Squamous Cell Cancer (SCC) Recurrent Laryngeal Nerve Palsy Deep Learning Postoperative Complication

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Left RLN lymph node (+)

Postoperative pathological results confirmed the metastasis of left recurrent laryngeal nerve lymph nodes.

No interventions assigned to this group

Left RLN lymph node (-)

Postoperative pathological results confirmed the negative of left recurrent laryngeal nerve lymph nodes.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Preoperative gastroscopic biopsy confirmed esophageal squamous cell carcinoma;
* The patient underwent esophagectomy with lymph nodes dissection along the left recurrent laryngeal nerve.

Exclusion Criteria

* The patient's medical records are incomplete;
* The patient refused to participate in the trial.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Daping Hospital

Chongqing, , China

Site Status

Countries

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China

Other Identifiers

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CEDREL-LNM

Identifier Type: -

Identifier Source: org_study_id

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