Trial Outcomes & Findings for Examining How a Text Message-based Educational Intervention Influences COVID-19 Testing (NCT NCT07074171)
NCT ID: NCT07074171
Last Updated: 2026-01-06
Results Overview
The number of participants who self-reported use of COVID-19 antigen test or PCR Test using individual-level data in the past 60 days
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
384 participants
Primary outcome timeframe
Baseline
Results posted on
2026-01-06
Participant Flow
Under the protocol, historical controls were not considered enrolled in this study, so they are not included in the enrollment number.
Participant milestones
| Measure |
Text Message-based Education Intervention
A text message-based COVID-19 education intervention with support from community health workers.
Text message-based education intervention: The intervention consisted of enhanced behavioral and educational text messages, up to three messages each week, providing updates on COVID-19 testing and vaccination. The text messages included digitally delivered intervention content such as a video with low-literacy instructions for administering the rapid antigen tests, guidance if they tested positive (e.g., quarantine, notify contacts, wearing a mask), and other relevant strategies and content focused on increasing COVID-19 testing and vaccination.
|
Historical Control Group
Participants in this Historical Control Group completed the prior Phase II embedded study, in which they received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys only.
Historical Control: Participants received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys as part of the Phase II embedded study.
|
|---|---|---|
|
Overall Study
STARTED
|
384
|
397
|
|
Overall Study
COMPLETED
|
349
|
397
|
|
Overall Study
NOT COMPLETED
|
35
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Examining How a Text Message-based Educational Intervention Influences COVID-19 Testing
Baseline characteristics by cohort
| Measure |
Text Message-based Education Intervention
n=384 Participants
A text message-based COVID-19 education intervention with support from community health workers.
Text message-based education intervention: The intervention consisted of enhanced behavioral and educational text messages, up to three messages each week, providing updates on COVID-19 testing and vaccination. The text messages included digitally delivered intervention content such as a video with low-literacy instructions for administering the rapid antigen tests, guidance if they tested positive (e.g., quarantine, notify contacts, wearing a mask), and other relevant strategies and content focused on increasing COVID-19 testing and vaccination.
|
Historical Control Group
n=397 Participants
Participants in this Historical Control Group completed the prior Phase II embedded study, in which they received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys only.
Historical Control: Participants received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys as part of the Phase II embedded study.
|
Total
n=781 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Customized
<= 18 years
|
2 Participants
n=37 Participants
|
4 Participants
n=56 Participants
|
6 Participants
n=82 Participants
|
|
Age, Customized
Between 18 and 65 years
|
279 Participants
n=37 Participants
|
291 Participants
n=56 Participants
|
570 Participants
n=82 Participants
|
|
Age, Customized
>= 65 years
|
102 Participants
n=37 Participants
|
91 Participants
n=56 Participants
|
193 Participants
n=82 Participants
|
|
Age, Customized
Unknown or Not Reported
|
1 Participants
n=37 Participants
|
11 Participants
n=56 Participants
|
12 Participants
n=82 Participants
|
|
Sex/Gender, Customized
Female
|
263 Participants
n=37 Participants
|
246 Participants
n=56 Participants
|
509 Participants
n=82 Participants
|
|
Sex/Gender, Customized
Male
|
121 Participants
n=37 Participants
|
150 Participants
n=56 Participants
|
271 Participants
n=82 Participants
|
|
Sex/Gender, Customized
Unknown or Not Reported
|
0 Participants
n=37 Participants
|
1 Participants
n=56 Participants
|
1 Participants
n=82 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
259 Participants
n=37 Participants
|
247 Participants
n=56 Participants
|
506 Participants
n=82 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
125 Participants
n=37 Participants
|
149 Participants
n=56 Participants
|
274 Participants
n=82 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=37 Participants
|
1 Participants
n=56 Participants
|
1 Participants
n=82 Participants
|
|
Region of Enrollment
United States
|
384 participants
n=37 Participants
|
397 participants
n=56 Participants
|
781 participants
n=82 Participants
|
PRIMARY outcome
Timeframe: BaselinePopulation: Data were only collected from participants who answered the question.
The number of participants who self-reported use of COVID-19 antigen test or PCR Test using individual-level data in the past 60 days
Outcome measures
| Measure |
Text Message-based Education Intervention
n=348 Participants
A text message-based COVID-19 education intervention with support from community health workers.
Text message-based education intervention: The intervention consisted of enhanced behavioral and educational text messages, up to three messages each week, providing updates on COVID-19 testing and vaccination. The text messages included digitally delivered intervention content such as a video with low-literacy instructions for administering the rapid antigen tests, guidance if they tested positive (e.g., quarantine, notify contacts, wearing a mask), and other relevant strategies and content focused on increasing COVID-19 testing and vaccination.
|
Historical Control Group
n=395 Participants
Participants in this Historical Control Group completed the prior Phase II embedded study, in which they received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys only.
Historical Control: Participants received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys as part of the Phase II embedded study.
|
|---|---|---|
|
Number of Participants Who Self-Reported Use of a COVID-19 Antigen or PCR Test
|
31 Participants
|
22 Participants
|
PRIMARY outcome
Timeframe: 8 weeksPopulation: Data were only collected from participants who answered the question.
The number of participants who self-reported use of COVID-19 antigen test or PCR Test using individual-level data in the past 60 days
Outcome measures
| Measure |
Text Message-based Education Intervention
n=348 Participants
A text message-based COVID-19 education intervention with support from community health workers.
Text message-based education intervention: The intervention consisted of enhanced behavioral and educational text messages, up to three messages each week, providing updates on COVID-19 testing and vaccination. The text messages included digitally delivered intervention content such as a video with low-literacy instructions for administering the rapid antigen tests, guidance if they tested positive (e.g., quarantine, notify contacts, wearing a mask), and other relevant strategies and content focused on increasing COVID-19 testing and vaccination.
|
Historical Control Group
n=394 Participants
Participants in this Historical Control Group completed the prior Phase II embedded study, in which they received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys only.
Historical Control: Participants received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys as part of the Phase II embedded study.
|
|---|---|---|
|
Number of Participants Who Self-Reported Use of a COVID-19 Antigen or PCR Test
|
60 Participants
|
46 Participants
|
SECONDARY outcome
Timeframe: BaselinePopulation: Data were only collected from participants who answered the question.
Outcome measures
| Measure |
Text Message-based Education Intervention
n=349 Participants
A text message-based COVID-19 education intervention with support from community health workers.
Text message-based education intervention: The intervention consisted of enhanced behavioral and educational text messages, up to three messages each week, providing updates on COVID-19 testing and vaccination. The text messages included digitally delivered intervention content such as a video with low-literacy instructions for administering the rapid antigen tests, guidance if they tested positive (e.g., quarantine, notify contacts, wearing a mask), and other relevant strategies and content focused on increasing COVID-19 testing and vaccination.
|
Historical Control Group
n=395 Participants
Participants in this Historical Control Group completed the prior Phase II embedded study, in which they received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys only.
Historical Control: Participants received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys as part of the Phase II embedded study.
|
|---|---|---|
|
Number of Participants Who Self-reported Receiving COVID-19 Vaccination
|
263 Participants
|
292 Participants
|
SECONDARY outcome
Timeframe: 8 weeksPopulation: Data were only collected from participants who answered the question.
Outcome measures
| Measure |
Text Message-based Education Intervention
n=349 Participants
A text message-based COVID-19 education intervention with support from community health workers.
Text message-based education intervention: The intervention consisted of enhanced behavioral and educational text messages, up to three messages each week, providing updates on COVID-19 testing and vaccination. The text messages included digitally delivered intervention content such as a video with low-literacy instructions for administering the rapid antigen tests, guidance if they tested positive (e.g., quarantine, notify contacts, wearing a mask), and other relevant strategies and content focused on increasing COVID-19 testing and vaccination.
|
Historical Control Group
n=391 Participants
Participants in this Historical Control Group completed the prior Phase II embedded study, in which they received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys only.
Historical Control: Participants received CDC-designed COVID-19 testing brochures and completed pre- and post-intervention surveys as part of the Phase II embedded study.
|
|---|---|---|
|
Number of Participants Who Self-reported Receiving COVID-19 Vaccination
|
259 Participants
|
12 Participants
|
SECONDARY outcome
Timeframe: Baseline, 8 weeksPopulation: Data were not collected for this outcome measure because the corresponding question was not included in the study survey. Therefore, no data were available for any participants. This outcome measure will not be collected in the future. The study protocol was not amended to reflect this.
Mitigation measures if a positive test is obtained include mask wearing, isolating, and notifying close contacts.
Outcome measures
Outcome data not reported
Adverse Events
Text Message-based Education Intervention
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Historical Control Group
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Belinda M Reininger, DrPH
The University of Texas Health Science Center at Houston
Phone: 956-755-0654
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place