Substance Use in Assault-Injured Young Adults

NCT ID: NCT07070414

Last Updated: 2025-11-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-08-31

Study Completion Date

2028-02-29

Brief Summary

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This study aims to improve a short motivational conversation to better help young adults who were injured in assaults and also use alcohol or cannabis. Researchers will gather both interview and survey data from young adults who came to the emergency department after an assault and currently use alcohol or cannabis. Guided by a theory about risky behaviors, the study will focus on how confident young people feel about making changes to their alcohol and cannabis use, and how their friends and family influence their alcohol and cannabis use and involvement in injuries from assault. The team will follow a step-by-step process used by the NIH to adapt and test the improved motivational conversation in the emergency department.

Detailed Description

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Aim 1: Quantitatively and qualitatively assess self-efficacy, perceived peer and familial norms, and motivation to reduce alcohol and/or cannabis use and engage in treatment referral, among assault-injured emerging adults. AIM 2: Adapt the BNI for use among assault-injured emerging adults with alcohol and/or cannabis misuse in the ED. AIM 3: Determine the feasibility and acceptability of an adapted BNI among assault-injured emerging adults with alcohol and/or cannabis misuse presenting to the ED through a randomized pilot trial comparing those who have received the adapted BNI and treatment referrals to a referrals-only control group. The focus of this registration is the randomized pilot in Aim 3. Anticipated start dates will be reflected in the clinical trial component in Aim 3.

Conditions

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Alcohol Misuse Cannabis Misuse

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Brief Negotiation Interview intervention (BNI) (adapted)

Participants randomized to the intervention arm will receive a brief motivational interview designed to increase motivation to reduce alcohol and/or cannabis use and engagement in treatment referral at 30-days. A referral includes a contact number to addiction treatment (primary care and/or specialty addiction care consistent with diagnostic criteria) and injury prevention services at the Yale Hospital Violence Intervention Program.

Group Type EXPERIMENTAL

Brief Negotiation Interview intervention (BNI) (adapted)

Intervention Type BEHAVIORAL

A brief motivational interview designed to increase motivation to reduce alcohol and/or cannabis use and engagement in treatment referral.

Control Group

Control group will receive contact referrals only. A referral includes a contact number to addiction treatment (primary care and/or specialty addiction care consistent with diagnostic criteria) and injury prevention services at the Yale Hospital Violence Intervention Program.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Brief Negotiation Interview intervention (BNI) (adapted)

A brief motivational interview designed to increase motivation to reduce alcohol and/or cannabis use and engagement in treatment referral.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Aim 1:

* Be clients of the Yale Hospital Violence Intervention Program (YHVIP)
* Be between the ages of 18-25 y/o upon study enrollment
* Have sustained an intentional injury inflicted by another person not considered to be a boy/girlfriend, fiancée, or spouse in the past year
* Report current alcohol and/or cannabis misuse
* Be English-speaking and able to provide informed consent.

Aim 2 and 3:

* Present to Yale New Haven Hospital ED for an intentional injury inflicted by another person not considered to be a boy/girlfriend, fiancée, or spouse
* Be between the ages of 18-25 y/o upon study enrollment
* Report current alcohol and/or cannabis misuse
* Be English-speaking and able to provide informed consent.

Exclusion Criteria

Aim 1:

* Be actively suicidal or severely cognitively impaired precluding informed consent
* Sustain an intentional injury from a boy/girlfriend, fiancée, or spouse or sexual assault
* Be incarcerated or in police custody
* Currently engaged in addiction treatment

Aim 2 and 3:

* Be actively suicidal or severely cognitively impaired precluding informed consent
* Sustain intentional injury from a boy/girlfriend, fiancée, spouse or by sexual assault
* Be incarcerated or in police custody
* Currently engaged in addiction treatment
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

Yale University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Edouard Coupet, MD, MS

Role: PRINCIPAL_INVESTIGATOR

Yale University

Locations

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Yale Department of Emergency Medicine

New Haven, Connecticut, United States

Site Status

Countries

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United States

Central Contacts

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Edouard Coupet Jr., MD, MS

Role: CONTACT

(203) 584-9445

Other Identifiers

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1R34DA061051-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

2000040490

Identifier Type: -

Identifier Source: org_study_id

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