Dexmedetomidine as an Additive for (Ipack)Block in Knee Surgery

NCT ID: NCT07058493

Last Updated: 2025-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-02

Study Completion Date

2024-07-30

Brief Summary

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Dexmedetomidine used as an Additive for Ipack Block in Knee Surgery

Detailed Description

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Many types of analgesia used but multimodal analgesia showed best results The interspace between the popliteal artery and capsule of the posterior knee (IPACK) block aims to blockade of sciatic nerve terminal branches for analgesia without motor affection

. (IPACK) block is a motor power sparing procedure that involves injecting local anesthetic into the space between the popliteal artery and the posterior capsule of the knee in order to treat posterior knee pain

Conditions

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Knee Surgeries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Bupivacaine

IPACK block with 20ml bupivacaine 0.25% alone.

.

Group Type EXPERIMENTAL

Bupivacaine

Intervention Type DRUG

20 ml of bupivacaine 0.25%.

Dexmedetomidine

IPACK block with 20 ml of bupivacaine 0.25% with dexmedetomidine 100 μg as adjuvant.

Group Type EXPERIMENTAL

Dexmedetomidine

Intervention Type DRUG

dexmedetomidine 100 μg as adjuvant to IPACK block with 20 ml of bupivacaine 0.25%.

Interventions

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Dexmedetomidine

dexmedetomidine 100 μg as adjuvant to IPACK block with 20 ml of bupivacaine 0.25%.

Intervention Type DRUG

Bupivacaine

20 ml of bupivacaine 0.25%.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 18-60 years
* ASA I, II .patients undergoing knee surgeries.

Exclusion Criteria

* patient Refusal
* bleeding disorders
* skin lesion
* infection
* known allergy
* contradictions of spinal anesthesia
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Dalia Ismail

Associate Professor of Anesthesia, Surgical ICU and pain management at Faculty of medicine Cairo University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dalia K Ismail

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Faculty of medicine Cairo university

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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MS-491-2023

Identifier Type: -

Identifier Source: org_study_id

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