A Comparative Study of the Efficacy and Safety of Telitacicept and Belimumab in the Treatment of Systemic Lupus Erythematosus Involving Multiple Units, Based on Previous Data.
NCT ID: NCT07053137
Last Updated: 2025-07-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
180 participants
OBSERVATIONAL
2025-05-01
2025-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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The Belimumab group
The participants in the study had previously used belimumab as a therapeutic drug.
No interventions assigned to this group
The Telitacicept group
The participants in the study had previously used telitacicept as a therapeutic drug.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Meets the revised SLE classification criteria of the American College of Rheumatology in 1997 or the SLE diagnostic classification criteria issued by EULAR/ACR in 2019;
* SELENA-SLEDAI score of at least 8 points (clinical symptoms of no less than 6 points, excluding positive anti-double-stranded DNA (anti-dsDNA) and low complement);
* Patients who have been using tofacitinib or belimumab for at least 12 weeks.
Exclusion Criteria
* eGFR \< 30 mL/min/1.73m², or undergoing hemodialysis or kidney transplantation;
* Pregnant women, or women planning to get pregnant in the near future while taking the medication, or lactating women;
* Participants who are simultaneously participating in other clinical studies;
* Patients who have received treatment with tixagrel or belimumab for less than 12 weeks.
18 Years
65 Years
ALL
No
Sponsors
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Renmin Hospital of Wuhan University
OTHER
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
OTHER
Beijing Friendship Hospital
OTHER
Yipeng Liu
OTHER
Responsible Party
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Yipeng Liu
Clinical Professor
Locations
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Qianfoshan Hospital
Jinan, Shandong, China
Countries
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Other Identifiers
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YXLL-KY-2025(101)
Identifier Type: -
Identifier Source: org_study_id
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