French Prospective Multicentric Study in Real World

NCT ID: NCT07039942

Last Updated: 2025-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

304 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-23

Study Completion Date

2027-04-30

Brief Summary

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The purpose of this postmarket clinical investigation is to evaluate the levels of glycemic control, quality of life, and satisfaction, as well as the patient experience, and acute diabetes complication rates provided by the Omnipod 5 Automated Insulin Delivery System (referred to as the Omnipod 5 System) in a real-world setting.

Detailed Description

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Twelve-month, real-world, non-interventional, prospective follow-up of adult and pediatric patients aged more than 2 years old, prescribed one of the Dexcom (Dexcom G6 or G7) configurations commercially available of the Omnipod 5 Automated Insulin Delivery System in France.

OPTIMAL-A study (Omnipod 5 - A French Prospective Multicentric Study in Real World), aims to provide the requisite real-world data on the glycemic control, quality of life, safety, and device usage profiles of users of the Omnipod 5 System during the 12 months after starting using Omnipod 5 in automated mode.

Conditions

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Diabetes Diabetes Mellitus Type 1 Diabetes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Omnipod 5 User

Participation of each patient begins at inclusion and continues until the end-of-study visit, 12 months (± 1 month) following first initiation of automated mode of the Omnipod 5 System

Omnipod 5

Intervention Type DEVICE

The Omnipod 5 Automated Insulin Delivery System (Omnipod 5 System) is a tubeless insulin pump with a mono-hormonal insulin delivery system designed to deliver U-100 insulin subcutaneously for the management of type 1 diabetes in people aged 2 years and older who require insulin.

The Omnipod 5 System is intended to function as an automated insulin delivery system when used with compatible Continuous Glucose Monitoring (CGM) systems.

Interventions

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Omnipod 5

The Omnipod 5 Automated Insulin Delivery System (Omnipod 5 System) is a tubeless insulin pump with a mono-hormonal insulin delivery system designed to deliver U-100 insulin subcutaneously for the management of type 1 diabetes in people aged 2 years and older who require insulin.

The Omnipod 5 System is intended to function as an automated insulin delivery system when used with compatible Continuous Glucose Monitoring (CGM) systems.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient with T1D aged ≥ 2 years.
* Patient prescribed a commercially available configuration of the Omnipod 5 System using a Dexcom sensor (Dexcom G6 or Dexcom G7).
* Patient has never used the Omnipod 5 System prior to inclusion.
* Patient has not objected to the use of their personal data for this study.
* Patient or legal guardian has an email address and mobile phone number.
* Patient (and legal guardians if the patient is a minor) is able to understand study information and Non-Opposition form.
* Patient (and legal guardians if the patient is a minor) is able to understand and complete questionnaires in French.
* Patient is covered by the local social security system.

Exclusion Criteria

* Patient is currently pregnant
* Patient presents an allergy to the materials of the Omnipod 5 System (patch, cannula, CGM).
* Patient is unable to be followed by the same investigation site for the duration of the study or is unwilling or unable to maintain contact with the healthcare professional.
* Patient is already participating in a clinical trial or in another study precluding their participation in other studies.
* Patient or legal guardian (for minors) is not able to understand and complete electronic questionnaires.
* Adult under guardianship, curatorship or tutorship.
* Adult otherwise deprived of liberty.
Minimum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Insulet Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Pierre RIVELINE, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Universitaire du Diabète et ses complications Hôpital Lariboisière

Locations

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CHU Angers

Angers, , France

Site Status RECRUITING

CHU Besançon - Hôpital de Jean Minjoz

Besançon, , France

Site Status RECRUITING

APHP Hopital Avicenne

Bobigny, , France

Site Status RECRUITING

CHU Bordeaux - Hôpital Pellegrin

Bordeaux, , France

Site Status NOT_YET_RECRUITING

CHU Bordeaux - Hôpital St-André

Bordeaux, , France

Site Status NOT_YET_RECRUITING

CHU BresCHU Brest - Hôpital de la Cavale Blanchet - Hôpital de la Cavale Blanche

Brest, , France

Site Status RECRUITING

Hôpital Femme Mère Enfant

Bron, , France

Site Status RECRUITING

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, , France

Site Status RECRUITING

CHU Dijon - Hôpital François MitterrandCHU Dijon - Hôpital François Mitterrand

Dijon, , France

Site Status RECRUITING

GH La Rochelle-Ré-Aunis - Hôpital Saint Louis

La Rochelle, , France

Site Status RECRUITING

APHP Hôpital Bicêtre

Le Kremlin-Bicêtre, , France

Site Status RECRUITING

Diab-eCare

Lyon, , France

Site Status RECRUITING

Institut de Diabétologie et de Nutrition du Centre

Mainvilliers, , France

Site Status RECRUITING

Fondation Ambroise Paré - Hôpital Européen de Marseille

Marseille, , France

Site Status RECRUITING

CHU Montpellier - Hôpital Arnaud de Villeneuve

Montpellier, , France

Site Status RECRUITING

CHU Montpellier - Hôpital Lapeyronie

Montpellier, , France

Site Status RECRUITING

CHU Orléans

Orléans, , France

Site Status RECRUITING

APHP Hôpital Lariboisière

Paris, , France

Site Status RECRUITING

APHP La Pitié Salpêtrière

Paris, , France

Site Status RECRUITING

Hôpital NECKER

Paris, , France

Site Status NOT_YET_RECRUITING

APHP Hopital Robert Debré

Paris, , France

Site Status RECRUITING

CH Périgueux

Périgueux, , France

Site Status RECRUITING

Cabinet Médical Saint-Cyr sur Loire

Saint-Cyr-sur-Loire, , France

Site Status RECRUITING

CHRU Strasbourg

Strasbourg, , France

Site Status NOT_YET_RECRUITING

Countries

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France

Central Contacts

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Trang Ly, MBBS, PhD

Role: CONTACT

978-600-7000

Bonnie Dumais Dumais, RN

Role: CONTACT

978-600-7000

Facility Contacts

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Lucie DUFOUR

Role: primary

Julie GUCCIARDI

Role: primary

Sarah YAHIAOUI

Role: primary

Caroline BOUYSSOU

Role: primary

Bogdan CATARGI

Role: primary

Pascale Quiniou

Role: primary

Karima RENDJA

Role: primary

Catherine PETIT

Role: primary

Isabelle SIMONEAU

Role: primary

Harivola ANDRIANTAOLO

Role: primary

Marie Agathe TROUVIN0

Role: primary

Sofia SEBAOUI

Role: primary

Eva BRIAND

Role: primary

Audrey OLIVETTI

Role: primary

Mérédith MERCIER

Role: primary

Manal AL MASRI-SHBAT

Role: primary

Sophie MIRAN

Role: primary

Charline POTIER

Role: primary

Marine Halbron

Role: primary

Jacques BELTRAND

Role: primary

Caroline ARNAUD-SARTHOU

Role: primary

Aude ANGELESCU

Role: primary

Magali LECOUTRE

Role: primary

Samir CHENAF

Role: primary

Other Identifiers

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OPTIMAL-A

Identifier Type: -

Identifier Source: org_study_id

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