E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

NCT ID: NCT07032350

Last Updated: 2025-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-22

Study Completion Date

2026-05-31

Brief Summary

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The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for their care recipients with dementia. The main questions it aims to answer are:

Is it feasible and acceptable for family caregivers to use the PACE-app?

Does using the PACE-app improve caregiver self-efficacy in pain management, adherence to pain treatments, communication with care providers, well-being, and their care recipient's pain conditions?

Researchers will compare caregivers who use the PACE-app to those who continue with their usual care practices to see if the app leads to better outcomes for both caregivers and care recipients.

Participants will:

Be randomly assigned to either the PACE-app group or a usual-care control group

Complete online surveys at baseline, 1 month, and 2 months

If assigned to the PACE-app group:

Use the PACE-app for 1 month to receive tailored pain management strategies and tools, and record their care recipient's pain in a digital diary

Participate in an interview about their experience with the app

All participation activities can be done remotely or in person.

Detailed Description

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This randomized controlled trial will assess the feasibility, usability, and preliminary efficacy of the Pain Control Enhancement App (PACE-app), a web-based intervention designed to support family caregivers of persons with dementia in managing pain. The trial will also explore mechanisms through which the PACE-app may affect caregiver and care recipient outcomes.

Uncontrolled pain is common in people with dementia and presents unique challenges for caregivers, particularly those with limited access to specialized healthcare services. Family caregivers often lack adequate knowledge, skills, and support to manage pain effectively, contributing to suboptimal outcomes for both caregivers and care recipients.

The PACE-app provides tailored, technology-based pain management support that includes:

Screening of caregiver-specific challenges in pain management;

Personalized pain management strategies based on the screening results;

Communication tools to facilitate interactions with healthcare providers;

A digital pain diary for tracking care recipients' pain experiences.

A total of 60 family caregivers of people with dementia and chronic pain will be randomized 1:1 to either the PACE-app intervention group or a usual-care control group. Participants in the intervention arm will use the app for 1 month and complete outcome assessments at baseline, 1 month (post-intervention), and 2 months (follow-up). Participants in the control arm will continue their usual caregiving practices and complete assessments on the same schedule.

Primary outcomes include feasibility (recruitment, retention, adherence to study protocol) and acceptability (measured by app usage analytics and qualitative interviews). Secondary outcomes include changes in caregiver self-efficacy in pain management, adherence to prescribed pain treatments, caregiver burden, stress, depression, and communication with healthcare providers. The study will also examine potential mediators (caregiver knowledge, communication) and moderators (caregiver characteristics, dementia severity, caregiving relationship) of intervention effects.

Additionally, the study will explore whether improvements in caregiver outcomes are associated with better outcomes for care recipients, such as reduced pain intensity and fewer urgent care visits related to pain.

Data collected will inform refinement of the PACE-app and guide the design of a future large-scale efficacy trial.

Conditions

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Care Giving Burden Dementia Chronic Pain Pain Management Palliative Care

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Usual Care Group

Care recipients will continue receiving their regular pain care. Caregivers will complete outcome assessments only.

Introductory Meeting (Baseline):

Caregivers will attend a 1.5-hour meeting to complete informed consent and baseline REDCap surveys.

Follow-up (Month 1 and Month 2):

At 1-month and 2-month follow-ups, caregivers will independently complete REDCap surveys (\~45 minutes per follow-up).

Group Type ACTIVE_COMPARATOR

Usual Pain Management Care

Intervention Type BEHAVIORAL

Caregivers receive no new intervention; they manage their care recipient's pain according to standard practices. No access to the PACE-app is given during the study period.

App Use Group

Care recipients will continue receiving their regular pain care. Caregivers will use the PACE-app and complete outcome assessments.

Introductory Meeting (Baseline):

Caregivers will attend a 1.5-hour meeting to complete informed consent and baseline REDCap surveys.

Intervention Period (Month 1):

Caregivers will use the PACE-app for 1 month, complete a daily pain diary (5-10 minutes/day), and access weekly summary reports to share with providers.

Post-Intervention (Month 1):

Caregivers will complete REDCap surveys and participate in a 1.5-hour interview on their experience with the app (audio-recorded unless declined).

Follow-up (Month 2):

Caregivers will complete the same REDCap questionnaires to assess longer-term outcomes.

Group Type EXPERIMENTAL

Web-based pain management support tool

Intervention Type OTHER

The Pain Control Enhancement App (PACE-app) is a web-based tool designed to help family caregivers manage pain in persons with dementia. The app provides a brief screening to identify caregiver challenges and delivers tailored strategies, communication prompts for providers, and an educational resource library. It includes a digital pain diary for tracking daily pain, treatments, and urgent care use, with weekly reports that can be shared with healthcare providers. The app is accessible on any internet-connected device and designed for caregivers with varying levels of digital literacy.

Interventions

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Web-based pain management support tool

The Pain Control Enhancement App (PACE-app) is a web-based tool designed to help family caregivers manage pain in persons with dementia. The app provides a brief screening to identify caregiver challenges and delivers tailored strategies, communication prompts for providers, and an educational resource library. It includes a digital pain diary for tracking daily pain, treatments, and urgent care use, with weekly reports that can be shared with healthcare providers. The app is accessible on any internet-connected device and designed for caregivers with varying levels of digital literacy.

Intervention Type OTHER

Usual Pain Management Care

Caregivers receive no new intervention; they manage their care recipient's pain according to standard practices. No access to the PACE-app is given during the study period.

Intervention Type BEHAVIORAL

Other Intervention Names

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PACE-app Usual Care

Eligibility Criteria

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Inclusion Criteria

* Be a primary caregiver - (a family member, relative, or friend) of a person with dementia (or cognitive impairment) and chronic pain (lasting \>3 months)'
* Be responsible for managing the care recipient's pain and pain treatments (including interpreting verbal or non-verbal pain communication).
* Be age 18 - 100.
* Be able to read and speak English.
* Have regular access to an electronic device (tablet, laptop, or computer) with internet connectivity (for using the app and participating in data collection).
* Be accessible by phone or email to schedule meetings.
* Be willing to commit to the full study duration and protocol.

Exclusion Criteria

* Currently participating in another research study that could interfere with this intervention.
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Alzheimer's Association

OTHER

Sponsor Role collaborator

University of Iowa

OTHER

Sponsor Role lead

Responsible Party

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Nai-Ching Chi

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nai-Ching Chi, PhD, MS, MSN, BSN

Role: PRINCIPAL_INVESTIGATOR

University of Iowa

Locations

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College of Nursing

Iowa City, Iowa, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Nai-Ching Chi, PhD, MS, BSN

Role: CONTACT

319-335-7064

Gabriel M Vald, MS, BA

Role: CONTACT

515-897-8517

Facility Contacts

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Nai-Ching Chi, PhD, MS, MSN, BSN

Role: primary

319-335-7064

Gabriel M Vald, MS, BA

Role: backup

515-897-8517

Other Identifiers

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AARGD-22-929062

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

202409203

Identifier Type: -

Identifier Source: org_study_id

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