Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals

NCT ID: NCT07022496

Last Updated: 2025-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

PHASE4

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-26

Study Completion Date

2025-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Caffeine extracted from green tea to abort acute attack of Migraine

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Caffeine tablets extracted from green tea can be used as caffeinated drinks to decrease intensity of migraine attacks

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Migraine Migraine Disease Migraine Headache Migraine Headache, With or Without Aura Migraine, Acute

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Caffeine group

Caffeine group added to standard treatment

Group Type EXPERIMENTAL

Caffeine (200 mg)

Intervention Type DRUG

caffeine tablets

triptans

Intervention Type DRUG

Sumatriptan

NSAID (Nonsteroidal anti-inflammatory drugs)

Intervention Type DRUG

Aspirin 250 mg, 81 mg, 75 mg

Paracetamol (acetaminophen)

Intervention Type DRUG

Paracetamol 250 mg

Control group

Standard treatment (NSAIDS, Triptans, or Acetaminophen)

Group Type ACTIVE_COMPARATOR

triptans

Intervention Type DRUG

Sumatriptan

NSAID (Nonsteroidal anti-inflammatory drugs)

Intervention Type DRUG

Aspirin 250 mg, 81 mg, 75 mg

Paracetamol (acetaminophen)

Intervention Type DRUG

Paracetamol 250 mg

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Caffeine (200 mg)

caffeine tablets

Intervention Type DRUG

triptans

Sumatriptan

Intervention Type DRUG

NSAID (Nonsteroidal anti-inflammatory drugs)

Aspirin 250 mg, 81 mg, 75 mg

Intervention Type DRUG

Paracetamol (acetaminophen)

Paracetamol 250 mg

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Patients suffering from migraine with aura, migraine without aura, episodic, and chronic migraine according to ICHD-3 diagnosis will be legible for the study.

Exclusion Criteria

Patients who have history of any cardiac dysrhythmia, hypertension, ischemic heart disease, active peptic ulcer disease, inflammatory bowel disease, obsessive compulsive disorder, pregnancy, breast-feeding, renal failure, hepatic failure, sleep disorder, mental retardation, and history of substance abuse that prevent them from cooperating with us during the study Patients who had headache due to: Cluster headache, trigeminal neuralgia, glossopharyngeal neuralgia, headache secondary to trauma, cranial disorder, vascular disorder, infection, or mass lesion, will also be excluded
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Nourhan Nader

Assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Ainshams university

Cairo, , Egypt

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Nourhan Nader Elguindy, Masters degree

Role: CONTACT

00201128215952

Diaa Marzouk Abdelhamid, PhD

Role: CONTACT

00201200678440

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Diaa Marzouk Abdelhamid, PhD

Role: primary

00201200678440

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

FMASU MD87/2023

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Migraine in Adolescents
NCT05654012 RECRUITING NA
Migraine Among Sohag University Students
NCT06536920 NOT_YET_RECRUITING