Study on the Effect of Digital Smoking Cessation Education Intervention on Outpatients

NCT ID: NCT07013084

Last Updated: 2025-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-12

Study Completion Date

2023-12-04

Brief Summary

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This study aimed to assess the novel approach of an immersive three-dimensional (3D) virtual reality (VR) smoking cessation program and its effectiveness on smoking outpatients

Detailed Description

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A randomized controlled trial (RCT) was conducted with 100 outpatients from a smoking cessation clinic in Taiwan. Participants were randomly assigned to either the experimental group (n=50) or the comparison group (n=50) through a coin toss. The experimental group received standard outpatient smoking cessation services in combination with an immersive 3D VR smoking cessation program, while the comparison group received only standard outpatient services. The VR program included five interactive modules that used immersive scenarios to simulate smoking-related cues and provide educational content, employing cognitive-behavioral techniques and practicing coping strategies to promote behavior change.

Conditions

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Smoking Cessation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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3D VR smoking cessation intervention

The program consists of five sequential VR modules, each structured as an interactive game scenario targeting specific aspects of smoking behavior and cessation motivation.

Group Type EXPERIMENTAL

3D VR smoking cessation program

Intervention Type BEHAVIORAL

Participants in the experimental group engaged with the VR system using a head-mounted display, allowing for full immersion in the virtual environment.

comparison group

no 3D VR smoking cessation program intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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3D VR smoking cessation program

Participants in the experimental group engaged with the VR system using a head-mounted display, allowing for full immersion in the virtual environment.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* currently receiving outpatient care at the smoking cessation clinic
* self-reported current tobacco use
* aged between 20 and 64 years
* no participation in any smoking cessation intervention within the past 12 months

Exclusion Criteria

\- Patients with medical contraindications that could prevent them from engaging with the VR equipment
Minimum Eligible Age

20 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tri-Service General Hospital

OTHER

Sponsor Role collaborator

National Taiwan Normal University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Tri-Service General Hospital SongShan Branch ,Taipei,Taiwan

Taipei, , Taiwan

Site Status

Countries

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Taiwan

References

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Reference Type RESULT
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Reference Type RESULT
PMID: 34533471 (View on PubMed)

Ebbert JO, Severson HH, Croghan IT, Danaher BG, Schroeder DR. Comparative effectiveness of the nicotine lozenge and tobacco-free snuff for smokeless tobacco reduction. Addict Behav. 2013 May;38(5):2140-5. doi: 10.1016/j.addbeh.2013.01.023. Epub 2013 Feb 4.

Reference Type RESULT
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Tonnesen P, Lauri H, Perfekt R, Mann K, Batra A. Efficacy of a nicotine mouth spray in smoking cessation: a randomised, double-blind trial. Eur Respir J. 2012 Sep;40(3):548-54. doi: 10.1183/09031936.00155811. Epub 2012 Feb 9.

Reference Type RESULT
PMID: 22323576 (View on PubMed)

Caponnetto P, Cibella F, Mancuso S, Campagna D, Arcidiacono G, Polosa R. Effect of a nicotine-free inhalator as part of a smoking-cessation programme. Eur Respir J. 2011 Nov;38(5):1005-11. doi: 10.1183/09031936.00109610. Epub 2011 May 12.

Reference Type RESULT
PMID: 21565921 (View on PubMed)

Ward KD, Asfar T, Al Ali R, Rastam S, Weg MW, Eissenberg T, Maziak W. Randomized trial of the effectiveness of combined behavioral/pharmacological smoking cessation treatment in Syrian primary care clinics. Addiction. 2013 Feb;108(2):394-403. doi: 10.1111/j.1360-0443.2012.04048.x. Epub 2012 Nov 19.

Reference Type RESULT
PMID: 22882805 (View on PubMed)

Karekla M, Savvides SN, Gloster A. An Avatar-Led Intervention Promotes Smoking Cessation in Young Adults: A Pilot Randomized Clinical Trial. Ann Behav Med. 2020 Oct 1;54(10):747-760. doi: 10.1093/abm/kaaa013.

Reference Type RESULT
PMID: 32383736 (View on PubMed)

Goldenhersch E, Thrul J, Ungaretti J, Rosencovich N, Waitman C, Ceberio MR. Virtual Reality Smartphone-Based Intervention for Smoking Cessation: Pilot Randomized Controlled Trial on Initial Clinical Efficacy and Adherence. J Med Internet Res. 2020 Jul 29;22(7):e17571. doi: 10.2196/17571.

Reference Type RESULT
PMID: 32723722 (View on PubMed)

Pericot-Valverde I, Secades-Villa R, Gutierrez-Maldonado J. A randomized clinical trial of cue exposure treatment through virtual reality for smoking cessation. J Subst Abuse Treat. 2019 Jan;96:26-32. doi: 10.1016/j.jsat.2018.10.003. Epub 2018 Oct 16.

Reference Type RESULT
PMID: 30466545 (View on PubMed)

Guo JL, Liao JY, Chang LC, Wu HL, Huang CM. The effectiveness of an integrated multicomponent program for adolescent smoking cessation in Taiwan. Addict Behav. 2014 Oct;39(10):1491-9. doi: 10.1016/j.addbeh.2014.05.009. Epub 2014 May 28.

Reference Type RESULT
PMID: 24949950 (View on PubMed)

Borrelli B, Rueras N, Jurasic M. Delivery of a smoking cessation induction intervention via virtual reality headset during a dental cleaning. Transl Behav Med. 2021 Feb 11;11(1):182-188. doi: 10.1093/tbm/ibz144.

Reference Type RESULT
PMID: 31665495 (View on PubMed)

Giovancarli C, Malbos E, Baumstarck K, Parola N, Pelissier MF, Lancon C, Auquier P, Boyer L. Virtual reality cue exposure for the relapse prevention of tobacco consumption: a study protocol for a randomized controlled trial. Trials. 2016 Feb 19;17:96. doi: 10.1186/s13063-016-1224-5.

Reference Type RESULT
PMID: 26892001 (View on PubMed)

Park CB, Choi JS, Park SM, Lee JY, Jung HY, Seol JM, Hwang JY, Gwak AR, Kwon JS. Comparison of the effectiveness of virtual cue exposure therapy and cognitive behavioral therapy for nicotine dependence. Cyberpsychol Behav Soc Netw. 2014 Apr;17(4):262-7. doi: 10.1089/cyber.2013.0253. Epub 2014 Feb 20.

Reference Type RESULT
PMID: 24555521 (View on PubMed)

Bordnick PS, Traylor AC, Carter BL, Graap KM. A Feasibility Study of Virtual Reality-Based Coping Skills Training for Nicotine Dependence. Res Soc Work Pract. 2012 May;22(3):293-300. doi: 10.1177/1049731511426880.

Reference Type RESULT
PMID: 25484549 (View on PubMed)

Pericot-Valverde I, Garcia-Rodriguez O, Gutierrez-Maldonado J, Ferrer-Garcia M, Secades-Villa R. Evolution of smoking urge during exposure through virtual reality. Stud Health Technol Inform. 2011;167:74-9.

Reference Type RESULT
PMID: 21685645 (View on PubMed)

Gamito P, Oliveira J, Baptista A, Morais D, Lopes P, Rosa P, Santos N, Brito R. Eliciting nicotine craving with virtual smoking cues. Cyberpsychol Behav Soc Netw. 2014 Aug;17(8):556-61. doi: 10.1089/cyber.2013.0329. Epub 2014 Mar 24.

Reference Type RESULT
PMID: 24660864 (View on PubMed)

Acker J, MacKillop J. Behavioral economic analysis of cue-elicited craving for tobacco: a virtual reality study. Nicotine Tob Res. 2013 Aug;15(8):1409-16. doi: 10.1093/ntr/nts341. Epub 2013 Jan 15.

Reference Type RESULT
PMID: 23322768 (View on PubMed)

Garcia-Rodriguez O, Weidberg S, Gutierrez-Maldonado J, Secades-Villa R. Smoking a virtual cigarette increases craving among smokers. Addict Behav. 2013 Oct;38(10):2551-4. doi: 10.1016/j.addbeh.2013.05.007. Epub 2013 May 23.

Reference Type RESULT
PMID: 23793042 (View on PubMed)

Gamito P, Oliveira J, Baptista A, Morais D, Lopes P, Saraiva T, Rosa P, Santos N, Soares F, Sottomayor C, Barata F. Nicotine craving: ERPs correlates after VR exposure to smoking cues. Stud Health Technol Inform. 2012;181:78-82.

Reference Type RESULT
PMID: 22954832 (View on PubMed)

Ramon JM, Nerin I, Comino A, Pinet C, Abella F, Carreras JM, Banque M, Baena A, Morchon S, Jimenez-Muro A, Marqueta A, Vilarasau A, Bullon R, Masuet-Aumatell C. A multicentre randomized trial of combined individual and telephone counselling for smoking cessation. Prev Med. 2013 Sep;57(3):183-8. doi: 10.1016/j.ypmed.2013.05.014. Epub 2013 Jun 1.

Reference Type RESULT
PMID: 23732247 (View on PubMed)

Free C, Knight R, Robertson S, Whittaker R, Edwards P, Zhou W, Rodgers A, Cairns J, Kenward MG, Roberts I. Smoking cessation support delivered via mobile phone text messaging (txt2stop): a single-blind, randomised trial. Lancet. 2011 Jul 2;378(9785):49-55. doi: 10.1016/S0140-6736(11)60701-0.

Reference Type RESULT
PMID: 21722952 (View on PubMed)

Morris CD, Waxmonsky JA, May MG, Tinkelman DG, Dickinson M, Giese AA. Smoking reduction for persons with mental illnesses: 6-month results from community-based interventions. Community Ment Health J. 2011 Dec;47(6):694-702. doi: 10.1007/s10597-011-9411-z. Epub 2011 May 10.

Reference Type RESULT
PMID: 21556784 (View on PubMed)

Reitzel LR, McClure JB, Cofta-Woerpel L, Mazas CA, Cao Y, Cinciripini PM, Vidrine JI, Li Y, Wetter DW. The efficacy of computer-delivered treatment for smoking cessation. Cancer Epidemiol Biomarkers Prev. 2011 Jul;20(7):1555-7. doi: 10.1158/1055-9965.EPI-11-0390. Epub 2011 May 25.

Reference Type RESULT
PMID: 21613389 (View on PubMed)

Other Identifiers

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C202005128

Identifier Type: -

Identifier Source: org_study_id

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