EUmetriosis: Insights Into the Pathogenesis of Endometriosis

NCT ID: NCT07000786

Last Updated: 2025-06-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-12

Study Completion Date

2029-12-31

Brief Summary

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This study investigates epigenetic changes in menstrual effluent and plasma from women with endometriosis to identify potential non-invasive diagnostic biomarkers for the disease.

Detailed Description

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Conditions

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Endometriosis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Epigenetics characterization

Group Type EXPERIMENTAL

Endometrial biopsy or menstrual cup and blood sample

Intervention Type PROCEDURE

Enrolled patients will give their menstrual effluent either via a menstrual cup or via a pipelle biopsy. They will also undergo a blood draw.

Interventions

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Endometrial biopsy or menstrual cup and blood sample

Enrolled patients will give their menstrual effluent either via a menstrual cup or via a pipelle biopsy. They will also undergo a blood draw.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Premenopausal
* In spontaneous menstrual cycle (no hormonal treatments for the last 3 months)
* Healthy or with a clear diagnosis of endometriosis via ultrasound, MRI or laparoscopy

Exclusion Criteria

* HIV or Hepatitis positive
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

56 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Université Catholique de Louvain

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Cliniques universitaires Saint-Luc

Brussels, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Marie-Madeleine Dolmans, MD, PhD

Role: CONTACT

+32 (0)2 764 5287

Facility Contacts

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Marie-Madeleine Dolmans, MD, PhD

Role: primary

+32 (0)2 764 5287

Other Identifiers

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EUmetriosis

Identifier Type: -

Identifier Source: org_study_id

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