Stone and Laser Therapies Post-Market Study (SALT)

NCT ID: NCT06982235

Last Updated: 2025-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

238 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-30

Study Completion Date

2029-02-28

Brief Summary

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The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g., transurethral or percutaneous access routes) or benign prostatic hyperplasia (BPH) treatment.

Detailed Description

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The SALT study is a multi-center, open label, non-randomized, prospective observational study to document on-going post-market safety and device performance data of BSC commercially available study devices that are used in diagnostic and/or therapeutic urinary tract procedures or surgical treatment for BPH.

Enrolled subjects undergoing diagnostic or therapeutic procedures using study devices will be followed for 1 year after the index procedure is complete.

Conditions

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Benign Prostate Hypertrophy(BPH) Renal Calculi Ureteral Stones, Kidney Stones Calculi, Urinary Urinary Tract Procedure

Keywords

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BPH Benign Prostatic Hyperplasia Lithotripsy Renal Calculi Renal Calculus Boston Scientific Kidney Stone Urinary Tract Procedure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Urinary Tract Procedure Cohort

Subjects intend to undergo diagnostic and/or therapeutic urinary tract procedure with study device(s)

Ureteroscope system

Intervention Type DEVICE

LithoVue™ Elite Single-Use Digital Flexible Ureteroscope System with intrarenal pressure monitoring

Laser system

Intervention Type DEVICE

Pulse™ 120H Holmium Laser System with MOSES™ 2.0 Technology

Benign Prostatic Hyperplasia Cohort

Subjects are at least 40 years of age diagnosed with BPH with lower urinary tract symptoms and intend to undergo BPH treatment with study device(s)

Laser system

Intervention Type DEVICE

Pulse™ 120H Holmium Laser System with MOSES™ 2.0 Technology

Interventions

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Ureteroscope system

LithoVue™ Elite Single-Use Digital Flexible Ureteroscope System with intrarenal pressure monitoring

Intervention Type DEVICE

Laser system

Pulse™ 120H Holmium Laser System with MOSES™ 2.0 Technology

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

For urinary tract procedure cohort:

1. Subject intends to undergo diagnostic and/or therapeutic urinary tract procedure with qualified BSC device(s)
2. Subject is willing and able to complete all follow-up visits

For BPH cohort:

1. Subject is ≥ 40 years of age
2. Subject with a diagnosis of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms
3. Subject intends to undergo BPH treatment with qualified BSC device(s)
4. Subject is willing and able to complete all follow-up visits

Exclusion Criteria

For urinary tract procedure cohort:

1. Subject requires simultaneous surgical treatment for BPH
2. Unwilling or unable to provide consent
3. Any other condition which, in the opinion of the investigator, precludes study participation (e.g., history of medical non-compliance, etc.)

For BPH cohort:

1. Subject requires simultaneous upper urinary calculi lithotripsy procedure (not applicable to bladder calculi)
2. Unwilling or unable to provide consent
3. Any other condition which, in the opinion of the investigator, precludes study participation (e.g., history of medical non-compliance, etc.)
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gita Ghadimi, OD

Role: STUDY_DIRECTOR

Boston Scientific Corporation

Locations

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University of Miami Hospital

Miami, Florida, United States

Site Status RECRUITING

University of South Florida

Tampa, Florida, United States

Site Status RECRUITING

Indiana University Medical Center

Indianapolis, Indiana, United States

Site Status RECRUITING

Duke University Medical Center

Durham, North Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Winnie Chen

Role: CONTACT

Phone: 952-930-6000

Email: [email protected]

Curtis Blackwell

Role: CONTACT

Phone: 952-930-6000

Facility Contacts

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Elena Cortez

Role: primary

Ray De La Morena Quirch

Role: primary

Alexander Czachor

Role: backup

Stephanie Wofford

Role: primary

Rebecca Schmidt

Role: primary

Other Identifiers

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U0777

Identifier Type: -

Identifier Source: org_study_id