Real-World Assessment of Therapeutic Strategies and Survival Outcomes Following First-Line Tislelizumab Therapy in Advanced Non-Small Cell Lung Cancer

NCT ID: NCT06962449

Last Updated: 2025-05-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-08-16

Study Completion Date

2026-12-31

Brief Summary

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This study is an observational study evaluating the treatment patterns and clinical outcomes after progression on first-line Tislelizumab treatment in advanced NSCLC. Based on the inclusion and exclusion criteria, patients with advanced NSCLC who received first-line Tislelizumab treatment and progressed will be retrospectively screened and collected from January 1, 2020, to the study initiation date, and followed up for observation.

Detailed Description

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Conditions

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Non-Small-Cell Lung Cancer Non-Small-Cell Lung Cancer Stage IV

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Histologically or cytologically confirmed unresectable locally advanced or metastatic NSCLC based on the 8th edition of the AJCC staging system.
* Previously received first-line treatment with Tislelizumab for advanced NSCLC.
* Medical records of disease progression after first-line treatment.

Exclusion Criteria

* Patients with incomplete key baseline and treatment information,including clinical stage, pathological type, treatment regimen, tumor assessment record after treatment ect.
* Patients included in anti-tumor drug intervention or unblinded clinical trials, in which the treatment being administered is unknown.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Chest Hospital

OTHER

Sponsor Role lead

Responsible Party

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Tianqing Chu

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shanghai Chest Hospital

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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IS24123

Identifier Type: -

Identifier Source: org_study_id

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