MagDI U.S. Registry

NCT ID: NCT06928545

Last Updated: 2025-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

106 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-28

Study Completion Date

2027-04-30

Brief Summary

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Assess the incidence and severity of internal hernia and bowel obstruction at one year in a U.S. population following use of the MagDI System to create side-to-side duodeno-ileal anastomoses.

Detailed Description

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Small bowel obstruction (SBO) following various abdominal and pelvic surgeries (0.4% - 13.9% at 5 years post-surgery) across obese and non-obese patients has been well studied in the scientific literature and found to be primarily due to intraperitoneal adhesions, with surgical technique (open surgery versus laparoscopic) cited as a key risk factor as reported in a retrospective population-based registry in Sweden (n=108,141). SBO incidence was reported as 3.2% for those undergoing bariatric surgery (n=1,896).

Given the MagDI System premarket clinical study (GTM-001) was conducted outside the U.S., FDA requires one post-market surveillance study to assess and characterize the incidence and severity of internal hernia and bowel obstruction in the U.S. intended use population treated with MagDI System. This study will be conducted through an observational patient registry and compare registry data to the premarket MagDI System clinical study data (GTM-001) and scientific literature. This post-market Registry Study was also a condition of the MagDI System FDA 510(k) clearances K242086 and K243359.

Conditions

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Anastomosis, Surgical Internal Hernia Bowel Obstruction

Keywords

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GT Metabolic MagDI System Magnetic Anastomosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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MagDI System

Participants who underwent the MagDI System procedure and consented to participate in the Registry

Side-to-side duodenal-ileal anastomosis

Intervention Type DEVICE

Side-to-side duodenal-ileal anastomosis formed by magnetic compression using the GT Metabolic MagDI System.

Interventions

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Side-to-side duodenal-ileal anastomosis

Side-to-side duodenal-ileal anastomosis formed by magnetic compression using the GT Metabolic MagDI System.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. \>21 years of age, at the time of informed consent.
2. Body Mass Index (BMI) between 30-50 kg/m2.
3. Indicated for a side-to-side duodeno-ileal anastomosis and is treated with the MagDI System at a U.S. registry center.
4. Participant has been informed of the nature of the registry.

Exclusion Criteria

1\. Participant does not provide informed consent to be enrolled and followed in the registry.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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GT Metabolic Solutions, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Ventura Advanced Surgical Associates

Ventura, California, United States

Site Status RECRUITING

Baptist Healthcare System, Inc.

Louisville, Kentucky, United States

Site Status RECRUITING

Ochsner Clinic Foundation

Lafayette, Louisiana, United States

Site Status RECRUITING

Bariatric Specialists of the Carolinas

Cary, North Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Lisa Griffin Vincent, PhD, MA

Role: CONTACT

Phone: +1 763-200-1416

Email: [email protected]

Josh Schumacher

Role: CONTACT

Phone: +1 763-200-1416

Email: [email protected]

Facility Contacts

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Hellmuth Billy

Role: primary

Candice Brunton

Role: primary

Ashunti Pearson

Role: primary

Jamie Lee Bull, PA

Role: primary

Other Identifiers

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GTM-007

Identifier Type: -

Identifier Source: org_study_id