The Impact of Manual Versus Mechanical Intestinal Suturing on the Incidence of Postoperative Complications Following Cystectomy With Ileal Conduit

NCT ID: NCT06928220

Last Updated: 2025-04-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-19

Study Completion Date

2025-04-07

Brief Summary

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Impact of Manual Versus Mechanical Intestinal Suturing on the Incidence and Management of Postoperative Complications in Patients Undergoing Radical Cystectomy with Ileal Conduit.

Detailed Description

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Currently, no specific trial compares hand-sewn intestinal anastomosis with mechanical stapled anastomosis in patients undergoing radical cystectomy with ileal conduit.

At Fundació Puigvert, approximately one hundred radical cystectomies with ileal conduit are performed annually. Due to the lack of evidence regarding the superiority of either intestinal anastomosis technique, the decision to use hand-sewn versus stapled anastomosis depends on the surgeon's expertise, without considering the potential impact of each technique on postoperative complication rates, surgical time, or functional outcomes.

Currently, no well-designed surgical trials demonstrate differences between hand-sewn and mechanical stapled anastomosis in radical cystectomy regarding intraoperative and postoperative complications. For this reason, the investigators will conduct a trial to assess the impact of each anastomosis technique

Conditions

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Bladder Cancer Anastomosis; Complications Ileus Paralytic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Manual anastamosis

Intestinal anastamosis will be performed manually

Group Type ACTIVE_COMPARATOR

cystectomy with ileal conduit, using manual bowel anastomosis

Intervention Type PROCEDURE

An ileal conduit will be the new storage area for urine once the bladder is removed.

Vycryl suture will be used to perform manual bowel anastomosis

Mechanical anastamosis

Intestinal anastamosis will be performed using stapling device

Group Type ACTIVE_COMPARATOR

cystectomy with ileal conduit, using mechanical bowel anastomosis

Intervention Type PROCEDURE

An ileal conduit will be the new storage area for urine once the bladder is removed.

GIA Device will be used to perform bowel anastomosis

Interventions

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cystectomy with ileal conduit, using mechanical bowel anastomosis

An ileal conduit will be the new storage area for urine once the bladder is removed.

GIA Device will be used to perform bowel anastomosis

Intervention Type PROCEDURE

cystectomy with ileal conduit, using manual bowel anastomosis

An ileal conduit will be the new storage area for urine once the bladder is removed.

Vycryl suture will be used to perform manual bowel anastomosis

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient who consents to participate and signs the informed consent.
* Patient candidate for radical open cystectomy and ileal conduit.

Exclusion Criteria

* Patient who is unable to complete the study questionnaires.
* Patient who has a life expectancy of less than 1 year.
* Candidate patients for other urinary diversions other than ileal conduit as a first option
* Candidate patients for laparoscopic or robotic cystectomy..
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundacio Puigvert

OTHER

Sponsor Role lead

Responsible Party

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Pavel Gavrilov

Consultant surgeon

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Fundacio Puigvert

Barcelona, Barcelona, Spain

Site Status

Countries

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Spain

Other Identifiers

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181184

Identifier Type: -

Identifier Source: org_study_id

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